A novel RNA-binding motif in influenza A virus non-structural protein 1

被引：0

作者：

Chen-ya Chien

Roberto Tejero

Yuanpeng Huang

Diane E. Zimmerman

Carlos B. Ríos

Robert M. Krug

Gaetano T. Montelione

机构：

[1] Rutgers University,Center for Advanced Biotechnology and Medicine

[2] Rutgers University,Department of Molecular Biology and Biochemistry

[3] Universidad de Valencia,Departamento de Quimica Fisica

来源：

Nature Structural Biology | 1997年 / 4卷

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D O I：

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学科分类号：

摘要：

The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold. Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2′ forms a novel arginine-rich nucleic acid binding motif.

引用

页码：891 / 895

页数：4

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