A novel mechanism for inhibiting proliferation of rheumatoid arthritis fibroblast-like synoviocytes: geniposide suppresses HIF-1α accumulation in the hypoxic microenvironment of synovium

被引：0
|
作者：
Peirong Gan
Minghui Sun
Hong Wu
Jiangtao Ke
Xintong Dong
Fangyuan Chen
机构：
[1] Anhui University of Chinese Medicine,College of Pharmacy
[2] Ministry of Education,Key Laboratory of Xin’an Medicine
[3] Anhui Province Key Laboratory of Research & Development of Chinese Medicine,undefined
来源：
Inflammation Research | 2022年 / 71卷
关键词：
Rheumatoid arthritis; Hypoxia; Fibroblast-like synoviocytes; Geniposide; Hypoxia inducible factor-1α; Proliferation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1375 / 1388
页数：13
相关论文
共 50 条
  • [21] Oridonin Inhibits Cell Proliferation and Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
    Cai-hong Shang
    Qing-qing Zhang
    Jian-hua Zhou
    Inflammation, 2016, 39 : 873 - 880
  • [22] CTGF promotes articular damage by increased proliferation of fibroblast-like synoviocytes in rheumatoid arthritis
    Ding, S.
    Duan, H.
    Fang, F.
    Shen, H.
    Xiao, W.
    SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2016, 45 (04) : 282 - 287
  • [23] Functional role of PPAR-γ on the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis
    Xiao-Feng Li
    Ying-Yin Sun
    Jing Bao
    Xin Chen
    Yu-Huan Li
    Yang Yang
    Lei Zhang
    Cheng Huang
    Bao-Ming Wu
    Xiao-Ming Meng
    Jun Li
    Scientific Reports, 7
  • [24] Oridonin Inhibits Cell Proliferation and Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
    Shang, Cai-hong
    Zhang, Qing-qing
    Zhou, Jian-hua
    INFLAMMATION, 2016, 39 (02) : 873 - 880
  • [25] Baicalein Inhibits Interleukin-1β-Induced Proliferation of Human Rheumatoid Arthritis Fibroblast-like Synoviocytes
    Chen, Shuo
    Yang, Yang
    Feng, Hui
    Wang, Hehong
    Zhao, Riguang
    Liu, Hongbin
    INFLAMMATION, 2014, 37 (01) : 163 - 169
  • [26] Baicalein Inhibits Interleukin-1β-Induced Proliferation of Human Rheumatoid Arthritis Fibroblast-like Synoviocytes
    Shuo Chen
    Yang Yang
    Hui Feng
    Hehong Wang
    Riguang Zhao
    Hongbin Liu
    Inflammation, 2014, 37 : 163 - 169
  • [27] MicroRNA-192 suppresses cell proliferation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes by downregulating caveolin 1
    Li, Supin
    Jin, Zhenmu
    Lu, Xiaobing
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2017, 432 (1-2) : 123 - 130
  • [28] MicroRNA-192 suppresses cell proliferation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes by downregulating caveolin 1
    Supin Li
    Zhenmu Jin
    Xiaobing Lu
    Molecular and Cellular Biochemistry, 2017, 432 : 123 - 130
  • [29] Amentoflavone Induces Ferroptosis to Alleviate Proliferation, Migration, Invasion and Inflammation in Rheumatoid Arthritis Fibroblast-like Synoviocytes by Inhibiting PIN1
    Ma, Yan
    Lin, Hongjun
    Li, Yunman
    An, Zhuoling
    CELL BIOCHEMISTRY AND BIOPHYSICS, 2025, 83 (01) : 1299 - 1312
  • [30] Imatinib inhibits CSF1R that stimulates proliferation of rheumatoid arthritis fibroblast-like synoviocytes
    Hu, X.
    Tang, J.
    Hu, X.
    Bao, P.
    Pan, J.
    Ou, Y.
    Deng, W.
    Liang, Y.
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2019, 195 (02): : 237 - 250
12345