A Practical Approach to Preventing Postoperative Recurrence in Crohn’s Disease

被引：17
作者：
Hashash J.G. [1 ]
Regueiro M. [1 ]
机构：
[1] Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, Mezzanine Level, C Wing, 200 Lothrop Street, Pittsburgh, 15213, PA
来源：
Current Gastroenterology Reports | 2016年 / 18卷 / 5期
关键词：
Anti-tumor necrosis factor; Immunomodulator; Postoperative Crohn’s disease; Prevention; Recurrence;
D O I：
10.1007/s11894-016-0499-8
中图分类号：
学科分类号：
摘要：
Postoperative Crohn’s disease recurrence remains common, and preventing additional surgery remains a challenge. A critical step to postoperative management of Crohn’s disease is being able to identify patients who should receive immediate postoperative therapy from the patients who can wait for recurrence prior to starting medications. All patients, regardless of their risk for recurrence, are advised to undergo a colonoscopy at 6 to 12 months after surgery to evaluate for endoscopic evidence of Crohn’s disease. Further management of patients depends on symptoms and the presence or absence of endoscopic recurrence. © 2016, Springer Science+Business Media New York.
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  • [1] Cosnes J., Nion-Larmurier I., Beaugerie L., Afchain P., Tiret E., Gendre J.P., Impact of the increasing use of immunosuppressants in Crohn’s disease on the need for intestinal surgery, Gut, 54, 2, pp. 237-241, (2005)
  • [2] D'Haens G.R., Geboes K., Peeters M., Baert F., Penninckx F., Rutgeerts P., Early lesions of recurrent Crohn’s disease caused by infusion of intestinal contents in excluded ileum, Gastroenterology, 114, 2, pp. 262-267, (1998)
  • [3] Olaison G., Smedh K., Sjodahl R., Natural course of Crohn’s disease after ileocolic resection: endoscopically visualised ileal ulcers preceding symptoms, Gut, 33, 3, pp. 331-335, (1992)
  • [4] Rutgeerts P., Geboes K., Vantrappen G., Beyls J., Kerremans R., Hiele M., Predictability of the postoperative course of Crohn’s disease, Gastroenterology, 99, 4, pp. 956-963, (1990)
  • [5] Sachar D.B., The problem of postoperative recurrence of Crohn’s disease, Med Clin N Am, 74, 1, pp. 183-188, (1990)
  • [6] Ng S.C., Kamm M.A., Management of postoperative Crohn’s disease, Am J Gastroenterol, 103, 4, pp. 1029-1035, (2008)
  • [7] Rutgeerts P., Review article: recurrence of Crohn’s disease after surgery—the need for treatment of new lesions, Aliment Pharmacol Ther, 24, pp. 29-32, (2006)
  • [8] Greenstein A.J., Lachman P., Sachar D.B., Springhorn J., Heimann T., Janowitz H.D., Et al., Perforating and non-perforating indications for repeated operations in Crohn’s disease: evidence for two clinical forms, Gut, 29, 5, pp. 588-592, (1988)
  • [9] Lautenbach E., Berlin J.A., Lichtenstein G.R., Risk factors for early postoperative recurrence of Crohn’s disease, Gastroenterology, 115, 2, pp. 259-267, (1998)
  • [10] Hanauer S.B., Korelitz B.I., Rutgeerts P., Peppercorn M.A., Thisted R.A., Cohen R.D., Et al., Postoperative maintenance of Crohn’s disease remission with 6-mercaptopurine, mesalamine, or placebo: a 2-year trial, Gastroenterology, 127, 3, pp. 723-729, (2004)
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