New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry

被引:0
作者
Stella Papachristou
Iliana Stamatiou
Anca P. Stoian
Nikolaos Papanas
机构
[1] Democritus University of Thrace,Diabetes Centre, Second Department of Internal Medicine
[2] “Carol Davila” University of Medicine,Diabetes, Nutrition and Metabolic Diseases Department
来源
Diabetes Therapy | 2021年 / 12卷
关键词
Corona virus infectious disease; Diabetes mellitus; Ketoacidosis; New-onset diabetes;
D O I
暂无
中图分类号
学科分类号
摘要
There is increasing evidence that coronavirus disease 2019 (COVID-19) may lead to new-onset diabetes mellitus (DM). This may occur even in patients without predisposing factors for impaired glucose metabolism. Both impaired pancreatic insulin secretion and insulin resistance have been implicated as underlying mechanisms. Importantly, new-onset hyperglycaemia is associated with worse prognosis in patients with COVID-19. Indeed, its prognosis may be even more sinister than in patients with pre-existing DM. More research data and knowledge are currently being collected to improve our insights into this constellation and to guide therapies in clinical reality.
引用
收藏
页码:461 / 464
页数:3
相关论文
共 71 条
[1]  
Wang D(2020)Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China JAMA 323 1061-1069
[2]  
Hu B(2006)Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS Diabetes Med 23 623-628
[3]  
Hu C(2016)Risk factors for primary Middle East respiratory syndrome coronavirus illness in humans, Saudi Arabia 2014 Emerg Infect Dis 22 49-55
[4]  
Yang JK(2020)Hyperglycemia without diabetes and new-onset diabetes are both associated with poorer outcomes in COVID-19 Diabetes Res Clin Pract 167 108382-1462
[5]  
Feng Y(2020)Diabetic ketoacidosis precipitated by COVID-19: a report of two cases and review of literature Diabetes Metab Syndr 14 1459-823
[6]  
Yuan MY(2020)Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics Diabetes Metab Res Rev 21 E3377-199
[7]  
Alraddadi BM(2020)SARS-CoV-2 inflammatory syndrome. Clinical features and rationale for immunological treatment Int J Mol Sci 24 816-775
[8]  
Watson JT(2004)Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited Arterioscler Thromb Vasc Biol 47 193-1432
[9]  
Almarashi A(2010)Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes Acta Diabetol 92 770-1125
[10]  
Singh AK(2020)Hyperglycemia, hydroxychloroquine, and the COVID-19 epidemic J Med Virol 43 1427-1515