Clinical burden of illness in patients with phenylketonuria (PKU) and associated comorbidities - a retrospective study of German health insurance claims data

被引:0
作者
K. F. Trefz
A. C. Muntau
K. M. Kohlscheen
J. Altevers
C. Jacob
S. Braun
W. Greiner
A. Jha
M. Jain
I. Alvarez
P. Lane
C. Schröder
F. Rutsch
机构
[1] Universitätsklinikum Heidelberg,Zentrum für Kinder
[2] University Children’s Hospital, und Jugendmedizin
[3] University Medical Center Hamburg-Eppendorf,Fakultät für Gesundheitswissenschaften
[4] Xcenda GmbH,Kinder
[5] Universität Bielefeld, und Jugendmedizin – Allgemeine Pädiatrie
[6] BioMarin Europe Ltd.,undefined
[7] BioMarin Deutschland GmbH,undefined
[8] Universitätsklinikum Münster,undefined
来源
Orphanet Journal of Rare Diseases | / 14卷
关键词
Phenylketonuria; Burden of illness; Burden of disease; Claims data; Statutory health insurance; Hyperphenylalaninemia;
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[1]  
Vockley J(2014)Phenylalanine hydroxylase deficiency: diagnosis and management guideline Genet Med 16 188-200
[2]  
Andersson HC(2013)Fluctuations in phenylalanine concentrations in phenylketonuria: a review of possible relationships with outcomes Mol Genet Metab 110 418-423
[3]  
Antshel KM(2017)The complete European guidelines on phenylketonuria: diagnosis and treatment Orphanet J Rare Dis. 12 162-54
[4]  
Braverman NE(1999)Rationale for the German recommendations for phenylalanine level control in phenylketonuria 1997 Eur J Pediatr 158 46-707
[5]  
Burton BK(2007)The response of patients with phenylketonuria and elevated serum phenylalanine to treatment with oral sapropterin dihydrochloride (6R-tetrahydrobiopterin): a phase II, multicentre, open-label, screening study J Inherit Metab Dis 30 700-707
[6]  
Frazier DM(2009)Efficacy of sapropterin dihydrochloride in increasing phenylalanine tolerance in children with phenylketonuria: a phase III, randomized, double-blind, placebo-controlled study J Pediatr 154 700-S418
[7]  
Cleary M(2008)Quality of life in noncompliant adults with phenylketonuria after resumption of the diet J Inherit Metab Dis 31 S415-38
[8]  
Trefz F(2018)Pegvaliase for the treatment of phenylketonuria: results of a long-term phase 3 clinical trial program (PRISM) Mol Genet Metab 124 27-57
[9]  
Muntau AC(2002)How practical are recommendations for dietary control in phenylketonuria? Lancet 360 55-150
[10]  
Feillet F(2015)Vitamin and mineral status in patients with hyperphenylalaninemia Mol Genet Metab 115 145-48