Serum hepatitis B virus DNA as a predictor of the development of cirrhosis and hepatocellular carcinoma

被引：12
|
作者：
Chen C.-J. [1 ]
Iloeje U.H. [1 ]
Yang H.-I. [1 ]
机构：
[1] Genomics Research Center, Academia Sinica, Nankang, Taipei 115
来源：
Current Hepatitis Reports | 2007年 / 6卷 / 1期
关键词：
Basal Core Promoter; Entry Examination; Haimen City;
D O I：
10.1007/BF02942173
中图分类号：
学科分类号：
摘要：
Chronic hepatitis B frequently progresses to cirrhosis and hepatocellular carcinoma. An elevated serum level of hepatitis B virus DNA is a major risk factor for cirrhosis and hepatocellular carcinoma, and there is a dose-response relationship between the serum hepatitis B virus DNA level and the risk of these complications. To lower the viral load to its lowest level is the method of choice to prevent major liver complications in chronic hepatitis B. Copyright © 2007 by Current Medicine Group LLC.
引用
收藏
页码：9 / 16
页数：7
相关论文
共 50 条
  • [31] Hepatocellular carcinoma in the absence of cirrhosis in patients with chronic hepatitis B virus infection
    Chayanupatkul, Maneerat
    Omino, Ronald
    Mittal, Sahil
    Kramer, Jennifer R.
    Richardson, Peter
    Thrift, Aaron P.
    El-Serag, Hashem B.
    Kanwal, Fasiha
    JOURNAL OF HEPATOLOGY, 2017, 66 (02) : 355 - 362
  • [32] Prevention of hepatitis B and C virus infection for prevention of cirrhosis and hepatocellular carcinoma
    Sung, JL
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 1997, 12 (9-10) : S370 - S376
  • [33] Hepatocellular carcinoma in the absence of cirrhosis in patients with chronic hepatitis B virus infection
    Xiang, Xiao
    You, Xue-Mei
    Zhong, Jian-Hong
    Li, Le-Qun
    JOURNAL OF HEPATOLOGY, 2017, 67 (04) : 885 - 886
  • [34] Incorporating Serum Level of Hepatitis B Surface Antigen or Omitting Level of Hepatitis B Virus DNA Does not Affect Calculation of Risk for Hepatocellular Carcinoma in Patients Without Cirrhosis
    Yang, Hwai-I
    Tseng, Tai-Chung
    Liu, Jessica
    Lee, Mei-Hsuan
    Liu, Chun-Jen
    Su, Tung-Hung
    Batrla-Utermann, Richard
    Chan, Henry Lik-Yuen
    Kao, Jia-Horng
    Chen, Chien-Jen
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2016, 14 (03) : 461 - +
  • [35] Relationship of hepatocellular carcinogenesis with precore mutant virus and serum hepatitis B virus DNA concentration - A longitudinal analysis of patients with cirrhosis
    Ikeda, K
    Saitoh, S
    Suzuki, Y
    Kobayashi, M
    Tsubota, A
    Fukuda, M
    Koida, I
    Arase, Y
    Chayama, K
    Murashima, N
    Kumada, H
    HEPATOLOGY RESEARCH, 1998, 10 (02) : 142 - 155
  • [36] The role of hepatitis B virus (HBV) in the development of hepatocellular carcinoma
    Hildt, E
    Hofschneider, PH
    Urban, S
    SEMINARS IN VIROLOGY, 1996, 7 (05): : 333 - 347
  • [37] Smoking, Hepatitis B Virus Infection, and Development of Hepatocellular Carcinoma
    Sherman, Morris
    Llovet, Josep M.
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2011, 103 (22): : 1642 - 1643
  • [38] Role of hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNA
    Claryssa Bianca
    Elizabeth Sidhartha
    Claudio Tiribelli
    Korri Elvanita El-Khobar
    Caecilia H C Sukowati
    World Journal of Hepatology, 2022, (05) : 866 - 884
  • [39] Role of hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNA
    Bianca, Claryssa
    Sidhartha, Elizabeth
    Tiribelli, Claudio
    El-Khobar, Korri Elvanita
    Sukowati, Caecilia H. C.
    WORLD JOURNAL OF HEPATOLOGY, 2022, 14 (05) : 866 - 884
  • [40] Hepatocellular carcinoma and hepatitis B virus
    Chan, HLY
    Sung, JJY
    SEMINARS IN LIVER DISEASE, 2006, 26 (02) : 153 - 161
12345