Borago officinalis L. flower: a comprehensive study on bioactive compounds and its health-promoting properties

被引：0
作者：
Ehsan Karimi
Ehsan Oskoueian
Afshin Karimi
Reza Noura
Mahdi Ebrahimi
机构：
[1] Islamic Azad University,Department of Biology, Faculty of Sciences, Mashhad Branch
[2] Mashhad Branch,Quality Department of Nutricia
[3] Agricultural Biotechnology Research Institute of Iran (ABRII),Department of Agriculture
[4] Agricultural Research,Department of Plant Science and Biotechnology, Faculty of Life Science and Biotechnology
[5] Education,Department of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine
[6] and Extension Organization (AREEO),undefined
[7] Mashhad Milk Powder Industrial,undefined
[8] Payame Noor University (PNU),undefined
[9] Shahid Beheshti University,undefined
[10] Universiti Putra Malaysia,undefined
来源：
Journal of Food Measurement and Characterization | 2018年 / 12卷
关键词：
Antibacterial; Anticancer; Anti-inflammatory; Antioxidant; Phenolics;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The herbal plant Borago officinalis L. flower were analysed for its bioactive compounds and antioxidant, antibacterial, anti-inflammatory and anticancer activities using different solvent polarities (methanol, ethanol and water). The RP-HPLC analyses of the methanolic extract confirmed the presence of phenolics (gallic acid, pyrogallol, salicylic acid, caffeic acid), flavonoids (myricetin, rutin) and isoflavonoid (daidzein). Besides, the major individual fatty acids of methanolic extract were α-linolenic, stearidonic, palmitic, linoleic and γ-linolenic acids. The methanolic extract possessed the highest antioxidant properties as compared to the ethanolic and water extracts. The flower methanolic, ethanolic and water extracts showed high, moderate and weak antibacterial activities against common human and foodborne pathogenic bacteria, respectively. Furthermore, the flower extracts showed weak anti-inflammatory in murine RAW 264.7 macrophage cells and low anticancer properties against human hepatic, prostate and colon cancer cells. This high-value flower could be considered as a source of putative antioxidant and antibacterial compounds to improve the human health and to be used as biopreservative in food and cosmetic industries.
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页码：826 / 838
页数：12
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