Three-component synthesis of 3,4-dihydroisoquinoline derivatives

被引:0
作者
Yu. V. Shklyaev
Yu. V. Nifontov
机构
[1] Institute of Technical Chemistry,Ural Branch of the Russian Academy of Sciences
来源
Russian Chemical Bulletin | 2002年 / 51卷
关键词
the Ritter reaction; the Baeyer reaction; 3,3-dimethyl-3,4-dihydroisoquinoline; isobutyraldehyde; nitriles; veratrole; 1,4-dimethoxybenzene; - and ; -xylenes; toluene; three-component synthesis;
D O I
暂无
中图分类号
学科分类号
摘要
A simple and convenient method for the synthesis of 1-substituted 3,3-dimethyl-3,4-dihydroisoquinolines was developed. The method is based on the [2+2+2] cyclization of alkyl- or alkoxybenzenes with isobutyraldehyde and nitriles.
引用
收藏
页码:844 / 849
页数:5
相关论文
共 50 条
  • [41] One pot three-component synthesis of 5-substituted 1H-tetrazole from aldehyde
    Mitra, Bijeta
    Mukherjee, Suvodip
    Pariyar, Gyan Chandra
    Ghosh, Pranab
    TETRAHEDRON LETTERS, 2018, 59 (14) : 1385 - 1389
  • [42] A Route to Alkenyl-Substituted 4-Hydroxypyridine and Pyrimidine Derivatives via Three-Component Access to β-Alkoxy-β-ketoenamides
    Bera, Mrinal K.
    Reissig, Hans-Ulrich
    SYNTHESIS-STUTTGART, 2010, (13): : 2129 - 2138
  • [43] Solvent-free copper-catalyzed three-component synthesis of 2-substituted quinazolin-4(3H)-ones
    Mehdi Soheilizad
    Shakiba Soroosh
    Rahim Pashazadeh
    Monatshefte für Chemie - Chemical Monthly, 2017, 148 : 739 - 743
  • [44] Solvent-free copper-catalyzed three-component synthesis of 2-substituted quinazolin-4(3H)-ones
    Soheilizad, Mehdi
    Soroosh, Shakiba
    Pashazadeh, Rahim
    MONATSHEFTE FUR CHEMIE, 2017, 148 (04): : 739 - 743
  • [45] Spirocyclohexadienones 7. Three-component condensation of 1- or 2-methoxynaphthalene with isobutyraldehyde and nitriles
    Nifontov, YV
    Glushkov, VA
    Shklyaev, YV
    RUSSIAN CHEMICAL BULLETIN, 2003, 52 (02) : 437 - 440
  • [46] Copper(II)-Catalyzed Three-Component Cascade Annulation of Diaryliodoniums, Nitriles, and Alkynes: A Regioselective Synthesis of Multiply Substituted Quinolines
    Wang, Yong
    Chen, Chao
    Peng, Jing
    Li, Ming
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (20) : 5323 - 5327
  • [47] A novel, one-pot, three-component synthesis of 4H-pyrido[1,2-a]pyrimidines
    Adib, Mehdi
    Sayahi, Mohammad Hosein
    Nosrati, Meisam
    Zhu, Long-Guan
    TETRAHEDRON LETTERS, 2007, 48 (24) : 4195 - 4198
  • [48] Three-component synthesis of 6-aryl-4-methyl-2-oxo-1,2,3,6-tetrahydropyrimidine-5-(N-aryl)carboxamides
    V. L. Gein
    T. M. Zamaraeva
    A. A. Kurbatova
    M. I. Vakhrin
    Chemistry of Heterocyclic Compounds, 2010, 46 : 856 - 858
  • [49] THREE-COMPONENT SYNTHESIS OF 6-ARYL-4-METHYL-2-OXO-1,2,3,6-TETRAHYDROPYRIMIDINE-5-(N-ARYL)CARBOXAMIDES
    Gein, V. L.
    Zamaraeva, T. M.
    Kurbatova, A. A.
    Vakhrin, M. I.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2010, 46 (07) : 856 - 858
  • [50] Base-Mediated Synthesis of Unsymmetrical 1,3,5-Triazin-2-amines via Three-Component Reaction of lmidates, Guanidines, and Amides or Aldehydes
    Pan, Liyang
    Li, Zhenxing
    Ding, Tao
    Fang, Xiaomin
    Zhang, Wenkai
    Xu, Hao
    Xu, Yuanqing
    JOURNAL OF ORGANIC CHEMISTRY, 2017, 82 (19) : 10043 - 10050