Three-component synthesis of 3,4-dihydroisoquinoline derivatives

被引:0
|
作者
Yu. V. Shklyaev
Yu. V. Nifontov
机构
[1] Institute of Technical Chemistry,Ural Branch of the Russian Academy of Sciences
来源
Russian Chemical Bulletin | 2002年 / 51卷
关键词
the Ritter reaction; the Baeyer reaction; 3,3-dimethyl-3,4-dihydroisoquinoline; isobutyraldehyde; nitriles; veratrole; 1,4-dimethoxybenzene; - and ; -xylenes; toluene; three-component synthesis;
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中图分类号
学科分类号
摘要
A simple and convenient method for the synthesis of 1-substituted 3,3-dimethyl-3,4-dihydroisoquinolines was developed. The method is based on the [2+2+2] cyclization of alkyl- or alkoxybenzenes with isobutyraldehyde and nitriles.
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页码:844 / 849
页数:5
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