The benefits of cement augmentation of pedicle screw fixation are increased in Osteoporotic bone: A finite element analysis

被引:23
作者
Wang W. [1 ]
Baran G.R. [1 ]
Garg H. [2 ]
Betz R.R. [3 ]
Moumene M. [4 ]
Cahill P.J. [3 ]
机构
[1] Department of Mechanical Engineering, College of Engineering, Temple University, Philadelphia, PA 19104
[2] Artemis Health Institute, Gurgaon 122001, Haryana
[3] Shriners Hospitals for Children-Philadelphia, Philadelphia, PA 19140
[4] DePuy Synthes Spine, Inc., Raynham, MA 02767
关键词
Cement; Finite element analysis; Osteoporosis; Pedicle screw; PMMA;
D O I
10.1016/j.jspd.2014.03.002
中图分类号
学科分类号
摘要
Study Design Biomechanical study using a finite element model of a normal and osteoporotic lumbar vertebrae comparing resistance with axial pullout and bending forces on polymethylmethacrylate-augmented and non-augmented pedicle screws. Objective To compare the effect of cement augmentation of pedicle screw fixation in normal and osteoporotic bone with 2 different techniques of cement delivery. Summary of Background Data Various clinical and biomechanical studies have addressed the benefits of cement augmentation of pedicle screws, but none have evaluated whether this effect is similar, magnified, or attenuated in osteoporotic bone compared with normal bone. In addition, no study has compared the biomechanical strength of augmented pedicle screws using cement delivery through the pedicle screw with delivery through a pilot hole. Methods This study was funded by a grant from DePuy Synthes Spine. Normal and osteoporotic lumbar vertebrae with pedicle screws were simulated. The models were tested for screw pullout strength with and without cement augmentation. Two methods of cement delivery were also tested. Both methods were tested using 1 and 2.5 cm 3 volume of cement infiltrated in normal and osteoporotic bone. Results The increase in screw pullout force was proportionally greater in osteoporotic bone with equivalent volumes of cement delivered. The researchers found that 1 and 2.5 cm3 of cement infiltrated bone volume resulted in an increase in pullout force by about 50% and 120% in normal bone, and by about 64% and 156% in osteoporotic bone, respectively. The delivery method had only a minimal effect on pullout force when 2.5 cm3 of cement was injected (<4% difference). Conclusions Cement augmentation increases the fixation strength of pedicle screws, and this effect is proportionately greater in osteoporotic bone. Cement delivery through fenestrated screws and delivery through a pilot hole result in comparable pullout strength at higher cement volumes. © 2014 Scoliosis Research Society.
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页码:248 / 259
页数:11
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共 42 条
  • [21] Shirazi-Adl A., Dammak M., Paiement G., Experimental determination of friction characteristics at the trabecular bone/porous-coated metal interface in cementless implants, J Biomed Mater Res, 27, pp. 167-175, (1993)
  • [22] Chevalier Y., Pahr D., Zysset P.K., The role of cortical shell and trabecular fabric in finite element analysis of the human vertebral body, J Biomech Eng, 131, (2009)
  • [23] Polikeit A., Nolte L.P., Ferguson S.J., Simulated influence of osteoporosis and disc degeneration on the load transfer in a lumbar functional spinal unit, J Biomech, 37, pp. 1061-1069, (2004)
  • [24] Augat P., Link T., Lang T.F., Et al., Anisotropy of the elastic modulus of trabecular bone specimens from different anatomical locations, Med Eng Phys, 20, pp. 124-131, (1998)
  • [25] Keaveny T.M., Buckley J.M., Biomechanics of vertebral bone, The Spine Technology Handbook, pp. 63-98, (2006)
  • [26] Polikeit A., Nolte L.P., Ferguson S.J., The effect of cement augmentation on the load transfer in an osteoporotic functional spinal unit: Finite-element analysis, Spine (Phila Pa 1976), 28, pp. 991-996, (2003)
  • [27] Diamant I., Shahar R., Masharawi Y., Et al., A method for patient-specific evaluation of vertebral cancellous bone strength: In vitro validation, Clin Biomech (Bristol, Avon), 22, pp. 282-291, (2007)
  • [28] Paxinos O., Tsitsopoulos P.P., Zindrick M.R., Et al., Evaluation of pullout strength and failure mechanism of posterior instrumentation in normal and osteopenic thoracic vertebrae, J Neurosurg Spine, 13, pp. 469-476, (2010)
  • [29] Becker S., Chavanne A., Spitaler R., Et al., Assessment of different screw augmentation techniques and screw designs in osteoporotic spines, Eur Spine J, 17, pp. 1462-1469, (2008)
  • [30] Takigawa T., Tanaka M., Konishi H., Et al., Comparative biomechanical analysis of an improved novel pedicle screw with sheath and bone cement, J Spinal Disord Tech, 20, pp. 462-467, (2007)