Evolution of antiglomerular basement membrane glomerulonephritis into membranous glomerulonephritis

被引：0
|
作者：
Natalie Hecht
Abiodun Omoloja
Dave Witte
Leonardo Canessa
机构：
[1] Wright State University Boonshoft School of Medicine,Department of Pediatrics
[2] University of Cincinnati,Department of Pathology
[3] The Children’s Medical Center,Department of Nephrology
来源：
Pediatric Nephrology | 2008年 / 23卷
关键词：
Anti-GBM antibody; Membranous glomerulonephritis;
D O I：
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学科分类号：
摘要：
Antiglomerular basement membrane glomerulonephritis (anti-GBM GN) is a rare disease characterized by autoantibodies to the alpha 3 chain of type IV collagen in the GBM. It is also known as Goodpasture’s syndrome when associated with pulmonary hemorrhage due to autoantibodies to the alpha 3 chain of type IV collagen also present in pulmonary alveoli. Even more rare is the evolution of anti-GBM GN into membranous nephropathy (MN). We report the management of a 9-year-old Caucasian girl with anti-GBM GN that evolved into MN and briefly review the literature.
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页码：477 / 480
页数：3
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