Molecular mechanisms of L-DOPA-induced dyskinesia

被引:0
作者
Peter Jenner
机构
[1] King's College London,
[2] Guy's Campus,undefined
[3] School of Health and Biomedical Sciences,undefined
来源
Nature Reviews Neuroscience | 2008年 / 9卷
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摘要
Dyskinesia is a treatment-limiting side effect of dopaminergic replacement therapies in Parkinson's disease. Here Jenner discusses what we know about the molecular causes of dyskinesia induction and expression, highlighting recent findings that suggest that altered glutamatergic transmission might be important.
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页码:665 / 677
页数:12
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