DNA methylation regulator-mediated modification patterns and risk of intracranial aneurysm: a multi-omics and epigenome-wide association study integrating machine learning, Mendelian randomization, eQTL and mQTL data

[1] Vlak M(2011)Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis Lancet Neurol 10 626-636

[2] Algra A(2007)Subarachnoid haemorrhage Lancet 369 306-318

[3] Brandenburg R(2013)The epidemiology of admissions of nontraumatic subarachnoid hemorrhage in the United States Neurosurgery 73 217-222

[4] Rinkel G(2016)Predictors of poor quality of life 1 year after subarachnoid hemorrhage Neurosurgery 78 256-264

[5] van Gijn J(2020)A clinically applicable deep-learning model for detecting intracranial aneurysm in computed tomography angiography images Nat Commun 11 6090-385

[6] Kerr RS(2021)A review on imaging techniques and quantitative measurements for dynamic imaging of cerebral aneurysm pulsations Sci Rep 11 2175-1469

[7] Rinkel GJ(2008)Dynamic regulation of estrogen receptor-alpha gene expression in the brain: a role for promoter methylation? Front Neuroendocrinol 29 375-401

[8] Rincon F(2005)Epigenetic transgenerational actions of endocrine disruptors and male fertility Science 308 1466-1070

[9] Rossenwasser RH(2022)Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease Sci Rep 15 19564-14124

[10] Dumont A(2006)Inherited epigenetic variation—revisiting soft inheritance Nat Rev Genet 7 395-657

[1] Vlak M(2011)Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis Lancet Neurol 10 626-636

[2] Algra A(2007)Subarachnoid haemorrhage Lancet 369 306-318

[3] Brandenburg R(2013)The epidemiology of admissions of nontraumatic subarachnoid hemorrhage in the United States Neurosurgery 73 217-222

[4] Rinkel G(2016)Predictors of poor quality of life 1 year after subarachnoid hemorrhage Neurosurgery 78 256-264

[5] van Gijn J(2020)A clinically applicable deep-learning model for detecting intracranial aneurysm in computed tomography angiography images Nat Commun 11 6090-385

[6] Kerr RS(2021)A review on imaging techniques and quantitative measurements for dynamic imaging of cerebral aneurysm pulsations Sci Rep 11 2175-1469

[7] Rinkel GJ(2008)Dynamic regulation of estrogen receptor-alpha gene expression in the brain: a role for promoter methylation? Front Neuroendocrinol 29 375-401

[8] Rincon F(2005)Epigenetic transgenerational actions of endocrine disruptors and male fertility Science 308 1466-1070

[9] Rossenwasser RH(2022)Elucidating the genetic architecture of DNA methylation to identify promising molecular mechanisms of disease Sci Rep 15 19564-14124

[10] Dumont A(2006)Inherited epigenetic variation—revisiting soft inheritance Nat Rev Genet 7 395-657