共 300 条
[1]
Wahid M(2018)Recent developments and obstacles in the treatment of melanoma with BRAF and MEK inhibitors Crit Rev Oncol Hematol 125 84-88
[2]
Jawed A(2017)Targeted agents and immunotherapies: optimizing outcomes in melanoma Nat Rev Clin Oncol 8 463-482
[3]
Mandal RK(2017)Three-year pooled analysis of factors associated with clinical outcomes across dabrafenib and trametinib combination therapy phase 3 randomised trials Eur J Cancer 82 45-55
[4]
Dar SA(2015)Improved overall survival in melanoma with combined dabrafenib and trametinib N Engl J Med 1 30-39
[5]
Akhter N(2016)Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial Lancet Oncol. 9 1248-1260
[6]
Somvanshi P(2018)Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial Lancet Oncol 5 603-615
[7]
Luke JJ(2012)Combinatorial therapies to overcome B-RAF inhibitor resistance in melanomas Future Medicine 13 2-424
[8]
Flaherty KT(2012)Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors Cancer Discov. 5 414-977
[9]
Ribas A(2012)Melanoma whole-exome sequencing identifies (V600E) B-RAF amplification-mediated acquired B-RAF inhibitor resistance Nat Commun 3 724-390
[10]
Long GV(2010)Melanomas acquires resistance to BRAF (V600E) inhibition by RTK or N-RAS upregulation Nature 7326 973-829