DL-3-n-butylphthalide promotes hippocampal neurogenesis and reduces mossy fiber sprouting in chronic temporal lobe epilepsy rats

[1] Helmstaedter C(2009)Chronic temporal lobe epilepsy: a neurodevelopmental or progressively dementing disease? Brain. 132 2822-2830

[2] Elger CE(2011)Cognitive impairments in patients with intractable temporal lobe epilepsy J Res Med Sci. 16 1466-1472

[3] Tavakoli M(2003)Do epileptic seizures damage the brain? Curr Opin Neurol. 16 189-195

[4] Barekatain M(2020)Cross talk between drug-resistant epilepsy and the gut microbiome Epilepsia. 61 2619-2628

[5] Doust HT(2019)L-NBP, a multiple growth factor activator, attenuates ischemic neuronal impairments possibly through promoting neuritogenesis Neurochem Int. 124 94-105

[6] Molavi H(2017)DL-3-n-butylphthalide induced neuroprotection, regenerative repair, functional recovery and psychological benefits following traumatic brain injury in mice Neurochem Int. 111 82-92

[7] Nouri RK(2018)L-3-n-butylphthalide regulates proliferation, migration, and differentiation of neural stem cell in vitro and promotes neurogenesis in APP/PS1 mouse model by regulating BDNF/TrkB/CREB/Akt pathway Neurotox Res. 34 477-488

[8] Moradi A(2019)Dl-3-n-butylphthalide reduces cognitive impairment induced by chronic cerebral hypoperfusion through GDNF/GFRα1/ret signaling preventing hippocampal neuron apoptosis Front Cell Neurosci. 13 351-1532

[9] Mehvari J(2018)Protective role of L-3-n-butylphthalide in cognitive function and dysthymic disorders in mouse with chronic epilepsy Front Pharmacol. 9 734-41

[10] Zare M(2016)CXCR4 antagonist AMD3100 suppresses the long-term abnormal structural changes of newborn neurons in the intraventricular kainic acid model of epilepsy Mol Neurobiol. 53 1518-490

[1] Helmstaedter C(2009)Chronic temporal lobe epilepsy: a neurodevelopmental or progressively dementing disease? Brain. 132 2822-2830

[2] Elger CE(2011)Cognitive impairments in patients with intractable temporal lobe epilepsy J Res Med Sci. 16 1466-1472

[3] Tavakoli M(2003)Do epileptic seizures damage the brain? Curr Opin Neurol. 16 189-195

[4] Barekatain M(2020)Cross talk between drug-resistant epilepsy and the gut microbiome Epilepsia. 61 2619-2628

[5] Doust HT(2019)L-NBP, a multiple growth factor activator, attenuates ischemic neuronal impairments possibly through promoting neuritogenesis Neurochem Int. 124 94-105

[6] Molavi H(2017)DL-3-n-butylphthalide induced neuroprotection, regenerative repair, functional recovery and psychological benefits following traumatic brain injury in mice Neurochem Int. 111 82-92

[7] Nouri RK(2018)L-3-n-butylphthalide regulates proliferation, migration, and differentiation of neural stem cell in vitro and promotes neurogenesis in APP/PS1 mouse model by regulating BDNF/TrkB/CREB/Akt pathway Neurotox Res. 34 477-488

[8] Moradi A(2019)Dl-3-n-butylphthalide reduces cognitive impairment induced by chronic cerebral hypoperfusion through GDNF/GFRα1/ret signaling preventing hippocampal neuron apoptosis Front Cell Neurosci. 13 351-1532

[9] Mehvari J(2018)Protective role of L-3-n-butylphthalide in cognitive function and dysthymic disorders in mouse with chronic epilepsy Front Pharmacol. 9 734-41

[10] Zare M(2016)CXCR4 antagonist AMD3100 suppresses the long-term abnormal structural changes of newborn neurons in the intraventricular kainic acid model of epilepsy Mol Neurobiol. 53 1518-490