Pharmacotherapy of Eating Disorders

被引:11
作者
Jackson, Cherry Wyant [1 ]
Cates, Marshall [1 ]
Lorenz, Raymond [2 ]
机构
[1] Univ Alabama Birmingham, Birmingham, AL 35294 USA
[2] Univ S Alabama, Mobile, AL 36688 USA
关键词
PLACEBO-CONTROLLED TRIAL; COGNITIVE-BEHAVIORAL THERAPY; BULIMIA-NERVOSA; ANOREXIA-NERVOSA; DOUBLE-BLIND; PHARMACOLOGICAL-TREATMENTS; SELF-HELP; FOLLOW-UP; BINGE; FLUOXETINE;
D O I
10.1177/0884533610362239
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Eating disorders are complex, chronic disorders that are difficult to treat. In addition, the 2 primary eating disorders, anorexia nervosa and bulimia nervosa, may have acute, life-threatening consequences. Medication trials for eating disorders have been hampered by high dropout rates, high placebo response, short trial duration, insufficient doses, and difficult outcome measures. Only 1 medication has been FDA approved for any eating disorder to date, and that is for fluoxetine in the treatment of bulimia. Clearly, new large-scale, independent studies using novel agents, and studying the use of medications for both short- and long-term outcomes, are needed. © 2010 American Society for Parenteral and Enteral Nutrition.
引用
收藏
页码:143 / 159
页数:17
相关论文
共 79 条
[1]  
AGRAS WS, 1994, J CLIN PSYCHIAT, V55, P179
[2]   WEIGHT-LOSS, COGNITIVE-BEHAVIORAL, AND DESIPRAMINE TREATMENTS IN BINGE-EATING DISORDER - AN ADDITIVE DESIGN [J].
AGRAS, WS ;
TELCH, CF ;
ARNOW, B ;
ELDREDGE, K ;
WILFLEY, DE ;
RAEBURN, SD ;
HENDERSON, J ;
MARNELL, M .
BEHAVIOR THERAPY, 1994, 25 (02) :225-238
[3]  
AGRAS WS, 1992, AM J PSYCHIAT, V149, P82
[4]  
ALEXANDER W, 1997, DRUG TOPICS, V141, P6
[5]  
[Anonymous], 1980, DSM 3
[6]  
[Anonymous], 2000, DIAGN STAT MAN MENT, DOI DOI 10.1176/APPI.BOOKS.9780890425787
[7]   A randomized, double-blind, placebo-controlled study of sibutramine in the treatment of binge-eating disorder [J].
Appolinario, JC ;
Bacaltchuk, J ;
Sichieri, R ;
Claudino, AM ;
Godoy-Matos, A ;
Morgan, C ;
Zanella, MT ;
Coutinho, W .
ARCHIVES OF GENERAL PSYCHIATRY, 2003, 60 (11) :1109-1116
[8]   A placebo-controlled, randomized trial of fluoxetine in the treatment of binge-eating disorder [J].
Arnold, LM ;
McElroy, SL ;
Hudson, JI ;
Welge, JA ;
Bennett, AJ ;
Keck, PE .
JOURNAL OF CLINICAL PSYCHIATRY, 2002, 63 (11) :1028-1033
[9]   Does fluoxetine augment the inpatient treatment of anorexia nervosa? [J].
Attia, E ;
Haiman, C ;
Walsh, T ;
Flater, SR .
AMERICAN JOURNAL OF PSYCHIATRY, 1998, 155 (04) :548-551
[10]   Use of nutritional supplements to increase the efficacy of fluoxetine in the treatment of anorexia nervosa [J].
Barbarich, NC ;
McConaha, CW ;
Halmi, KA ;
Gendall, K ;
Sunday, SR ;
Gaskill, J ;
La Via, M ;
Frank, GK ;
Brooks, S ;
Plotnicov, KH ;
Kaye, WH .
INTERNATIONAL JOURNAL OF EATING DISORDERS, 2004, 35 (01) :10-15