2(S),6(R)-Dimethyl-4-(4-methoxyphenyl)-5(R)-ethyl-3-cyclohexene-1(S)-carboxylic acid and its enantiomer:: potential therapeutic agents for prostate cancer

被引：8
作者：
Xie, SW
Hou, YQ
Meyers, CY
Robinson, PD [1 ]
机构：
[1] So Illinois Univ 4324, Dept Geol, Carbondale, IL 62901 USA
[2] So Illinois Univ 4409, Dept Chem & Biochem, Meyers Inst Fundamental Res Organ & Med Chem, Carbondale, IL 62901 USA
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2002年 / 58卷
关键词：
D O I：
10.1107/S1600536802021748
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The synthesis, isolation, and definitive diasteriomeric characterization of the racemic title compound, C18H24O3, (I), was accomplished. The two enantiomers are hydrogen bonded through their respective carboxylic acid groups, forming an octagonal bridge. A preliminary study indicates that (I) definitely inhibits prostate cancer-cell proliferation.
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收藏
页码：O1460 / O1462
页数：3
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