Structure Elucidation at the Nanomole Scale. 3. Phorbasides G-I from Phorbas sp.

被引：31

作者：

Dalisay, Doralyn S. ^{[1
]}

Molinski, Tadeusz F. ^{[1
,2
]}

机构：

[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

[2] Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 04期

关键词：

MARINE SPONGE; NATURAL-PRODUCTS; ABSOLUTE-CONFIGURATION; MACROLIDES; PHORBOXAZOLES; CD;

D O I：

10.1021/np1000297

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new phorbasides (G-I), chlorocyclopropyl ene-yne macrolide glycosides, were isolated from the sponge Phorbas sp. in yields of 7-9.5 mu g and fully characterized by MS, CD, and microcryoprobe NMR. The structures of the new compounds differ only in the nature of the sugar residues. The absolute configurations of the new compounds were correlated by ROESY and CD with the parent compounds phorbasides A and B.

引用

页码：679 / 682

页数：4

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