Polymeric Micelles as Novel Carriers for Poorly Soluble Drugs-A Review

被引：51

作者：

Reddy, B. Pavan Kumar ^{[1
]}

Yadav, Hemant K. S. ^{[1
]}

Nagesha, Dattatri K. ^{[1
]}

Raizaday, Abhay ^{[1
]}

Karim, Abdul ^{[1
]}

机构：

[1] JSS Univ, JSS Coll Pharm, Dept Pharmaceut, Mysore 570015, Karnataka, India

来源：

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2015年 / 15卷 / 06期

关键词：

Polymeric Micelles; Poorly Soluble Drug; Nanoparticles; Critical Micelle Concentration and Poly(ethylene oxide)-Poly(propylene oxide)-Poly(ethylene oxide); BLOCK-COPOLYMER MICELLES; POLYION COMPLEX MICELLES; METHOXY POLY(ETHYLENE GLYCOL); DIBLOCK COPOLYMERS; DELIVERY; WATER; INDOMETHACIN; FLUORESCENCE; DESIGN; CORE;

D O I：

10.1166/jnn.2015.9713

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Polymeric micelles are used as 'smart drug carriers' for targeting certain areas of the body by making them stimuli-sensitive or by attachment of a specific ligand molecule onto their surface. The main aim of using polymeric micelles is to deliver the poorly water soluble drugs. Now-a-days they are used especially in the areas of cancer therapy also. In this article we have reviewed several aspects of polymeric micelles concerning their mechanism of formation, chemical nature, preparation and characterization techniques, and their applications in the areas of drug delivery.

引用

页码：4009 / 4018

页数：10

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