A new cytotoxic iridoid from Callicarpa nudiflora

被引：36

作者：

Mei, Wen-Li ^{[1
]}

Han, Zhuang ^{[1
]}

Cui, Hai-Bin ^{[1
]}

Zhao, You-Xing ^{[2
]}

Deng, Yuan-Yuan ^{[1
]}

Dai, Hao-Fu ^{[1
]}

机构：

[1] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Hainan, Peoples R China

[2] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Yunnan, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2010年 / 24卷 / 10期

关键词：

Callicarpa nudiflora; iridoid; nudifloside; cytotoxicity; CONSTITUENTS; MACROPHYLLA; PEDUNCULATA; LEAVES;

D O I：

10.1080/14786410802267544

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new iridoid, named nudifloside (1), together with three known compounds, was isolated from the EtOH extract of the aerial parts of Callicarpa nudiflora Hook. The structures were elucidated by a study of their physical and spectral data. Nudifloside (1) and the isolated known compound linearoside (2) displayed inhibitory effects towards chronic myelogenous leukaemia K562 cell line, with IC50 values of 20.7 and 36.0 mu g mL-1, respectively.

引用

页码：899 / 904

页数：6

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