Excitability of the motor cortical representation of the external anal sphincter

被引:17
作者
Lefaucheur, JP [1 ]
机构
[1] Hop Henri Mondor, Assistance Publ Hop Paris, Serv Physiol Explorat Fonct, F-94010 Creteil, France
关键词
anal sphincter; clinical neurophysiology; cortical excitability; electromyographic silent period; motor cortex; motor-evoked potentials; paired pulses; transcranial magnetic stimulation;
D O I
10.1007/s00221-004-2170-0
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This study was designed to assess the excitability of the motor cortical representation of the external anal sphincter by using transcranial magnetic stimulation (TMS). In six healthy volunteers, the rest motor threshold and the duration of the cortical silent period were determined with single TMS pulses, and the intracortical inhibition and facilitation were measured with paired TMS pulses. Values obtained from the anal sphincter were compared with those obtained from a muscle in the right hand. All subjects completed the study. Rest motor threshold and intracortical facilitation were similar in both muscles. In contrast, cortical silent period duration and intra-cortical inhibition were less for the anal sphincter than for hand muscle. This study has opened new perspectives for the investigation of anal sphincter cortical control in humans.
引用
收藏
页码:268 / 272
页数:5
相关论文
共 46 条
[1]   Clinical and research methods for evaluating cortical excitability [J].
Abbruzzese, G ;
Trompetto, C .
JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2002, 19 (04) :307-321
[2]  
Boroojerdi B, 2000, MUSCLE NERVE, V23, P1594, DOI 10.1002/1097-4598(200010)23:10<1594::AID-MUS19>3.0.CO
[3]  
2-3
[4]   Stroke and incontinence [J].
Brittain, KR ;
Peet, SM ;
Castleden, CM .
STROKE, 1998, 29 (02) :524-528
[5]   CORTICOSPINAL PROJECTIONS TO UPPER AND LOWER-LIMB SPINAL MOTONEURONS IN MAN [J].
BROUWER, B ;
ASHBY, P .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1990, 76 (06) :509-519
[6]  
CANTELLO R, 1992, NEUROLOGY, V42, P1951
[7]   Intracortical inhibition and facilitation in different representations of the human motor cortex [J].
Chen, R ;
Tam, A ;
Bütefisch, C ;
Corwell, B ;
Ziemann, U ;
Rothwell, JC ;
Cohen, LG .
JOURNAL OF NEUROPHYSIOLOGY, 1998, 80 (06) :2870-2881
[8]  
Cruccu G, 1997, MUSCLE NERVE, V20, P418, DOI 10.1002/(SICI)1097-4598(199704)20:4<418::AID-MUS3>3.0.CO
[9]  
2-D
[10]   Intracortical inhibition and facilitation of the response of the diaphragm to transcranial magnetic stimulation [J].
Demoule, A ;
Verin, E ;
Ross, E ;
Moxham, J ;
Derenne, JP ;
Polkey, MI ;
Similowski, T .
JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2003, 20 (01) :59-64