Low-Intensity Pulsed Ultrasound Stimulation for Bone Fractures Healing A Review

被引：49

作者：

Palanisamy, Poornima ^{[1
]}

Alam, Monzurul ^{[1
]}

Li, Shuai ^{[1
]}

Chow, Simon K. H. ^{[2
]}

Zheng, Yong-Ping ^{[1
]}

机构：

[1] Hong Kong Polytech Univ, Dept Biomed Engn, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Dept Orthopaed & Traumatol, Hong Kong, Peoples R China

来源：

JOURNAL OF ULTRASOUND IN MEDICINE | 2022年 / 41卷 / 03期

关键词：

bone healing; delayed unions; fresh fractures; low‐ intensity pulsed ultrasound; nonunions; ultrasound therapy; POWER DOPPLER ULTRASONOGRAPHY; DISTRACTION OSTEOGENESIS; DOUBLE-BLIND; MATRIX METALLOPROTEINASES; TREATMENT TIME; DELAYED UNION; LIPUS; ANGIOGENESIS; CALLUS; EXPRESSION;

D O I：

10.1002/jum.15738

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

Low-intensity pulsed ultrasound (LIPUS) is a developing technology, which has been proven to improve fracture healing process with minimal thermal effects. This noninvasive treatment accelerates bone formation through various molecular, biological, and biomechanical interactions with tissues and cells. Although LIPUS treatment has shown beneficial effects on different bone fracture locations, only very few studies have examined its effects on deeper bones. This study provides an overview on therapeutic ultrasound for fractured bones, possible mechanisms of action, clinical evidences, current limitations, and its future prospects.

引用

页码：547 / 563

页数：17

共 133 条

[1]

Agarwal A, 2010, EDUC HEALTH, V23, P225

[2] Role of Chondrocytes in Cartilage Formation, Progression of Osteoarthritis and Cartilage Regeneration [J].

Akkiraju, Hemanth ;

Nohe, Anja .

JOURNAL OF DEVELOPMENTAL BIOLOGY, 2015, 3 (04) :177-192

[3] ULTRASONIC ENERGY AND SURGICALLY PRODUCED DEFECTS IN BONE [J].

ARDAN, NI ;

JANES, JM ;

HERRICK, JF .

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1957, 39 (02) :394-402

[4]

Aubin J.E., 2001, PARATHYROIDS, V2nd, P199

[5] Low-intensity pulsed ultrasound accelerates rat femoral fracture healing by acting on the various cellular reactions in the fracture callus [J].

Azuma, Y ;

Ito, M ;

Harada, Y ;

Takagi, H ;

Ohta, T ;

Jingushi, S .

JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 (04) :671-680

[6] Low-intensity pulsed ultrasound (LIPUS) induces RANKL, MCP-1, and MIP-1β expression in osteoblasts through the angiotensin II type 1 receptor [J].

Bandow, Kenjiro ;

Nishikawa, Yoshiaki ;

Ohnishi, Tomokazu ;

Kakimoto, Kyoko ;

Soejima, Kazuhisa ;

Iwabuchi, Sadahiro ;

Kuroe, Kazuto ;

Matsuguchi, Tetsuya .

JOURNAL OF CELLULAR PHYSIOLOGY, 2007, 211 (02) :392-398

[7]

Barth G., 1949, STRAHLENTHER ONKOL, V79, P98

[8] Experience of an isolated use of low-intensity pulsed ultrasound therapy on fracture healing in established non-unions: a prospective case series [J].

Bawale, Rajesh ;

Segmeister, Markus ;

Sinha, Sanjay ;

Shariff, Sajid ;

Singh, Bijayendra .

JOURNAL OF ULTRASOUND, 2021, 24 (03) :249-252

[9]

BENDER L F, 1954, Arch Phys Med Rehabil, V35, P555

[10] Failed treatment of long bone nonunions with low intensity pulsed ultrasound [J].

Biglari, Bahram ;

Yildirim, Timur Mert ;

Swing, Tyler ;

Bruckner, Thomas ;

Danner, Wolfgang ;

Moghaddam, Arash .

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 2016, 136 (08) :1121-1134

← 1 2 3 4 5 6 7 8 9 10 →