International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem

被引：78

作者：

Sanchez-Borges, Mario ^{[1
,2
]}

Fernandez-Caldas, Enrique ^{[3
,4
]}

Thomas, Wayne R. ^{[5
]}

Chapman, Martin D. ^{[6
]}

Lee, Bee Wah ^{[7
]}

Caraballo, Luis ^{[8
]}

Acevedo, Nathalie ^{[9
]}

Chew, Fook Tim ^{[10
]}

Ansotegui, Ignacio J. ^{[11
]}

Behrooz, Leili ^{[12
]}

Phipatanakul, Wanda ^{[12
]}

van Wijk, Roy Gerth ^{[13
]}

Pascal, Demoly ^{[14
,15
]}

Rosario, Nelson ^{[16
]}

Ebisawa, Motohiro ^{[17
]}

Geller, Mario ^{[18
]}

Quirce, Santiago ^{[19
,20
]}

Vrtala, Susanne ^{[21
]}

Valenta, Rudolf ^{[21
]}

Ollert, Markus ^{[22
]}

Canonica, Giorgio Walter ^{[23
]}

Calderon, Moises A. ^{[24
]}

Barnes, Charles S. ^{[25
]}

Custovic, Adnan ^{[26
]}

Benjaponpitak, Suwat ^{[27
]}

Capriles-Hulett, Arnaldo ^{[1
]}

机构：

[1] Ctr Med Docente Trinidad, Allergy & Clin Immunol Dept, Caracas, Venezuela

[2] Clin El Avila, 6a Transversal Urb Altamira,Piso 8,Consultoria 80, Caracas 1060, Venezuela

[3] Inmunotek SL, Madrid, Spain

[4] Univ S Florida, Coll Med, Div Allergy & Immunol, Tampa, FL USA

[5] Univ Western Australia, Telethon Kids Inst, Crawley, WA, Australia

[6] Indoor Biotechnol, Charlottesville, VA USA

[7] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Paediat, Singapore, Singapore

[8] Univ Cartagena, Inst Immunol Res, Cartagena, Colombia

[9] Univ Cartagena, Cartagena, Colombia

[10] Natl Univ Singapore, Dept Biol Sci, Allergy & Mol Immunol Lab, Funct Genom Labs, Singapore, Singapore

[11] Hosp Quiron Bizkaia, Dept Allergy & Immunol, Bilbao, Spain

[12] Harvard Med Sch, Boston Cshildrens Hosp, Div Immunol & Allergy, Boston, MA USA

[13] Erasmus MC, Dept Internal Med, Allergol, Rotterdam, Netherlands

[14] Univ Hosp Montpellier, Dept Pulmonol, Div Allergy, Paris, France

[15] Sorbonne Univ, Montpellier & Pierre Louis Inst Epidemiol & Publ, Paris, France

[16] Univ Fed Parana, Rua Gen Carneiro, Curitiba, Parana, Brazil

[17] Sagamihara Natl Hosp, Clin Res Ctr Allergol & Rheumatol, Dept Allergy, Sagamihara, Kanagawa, Japan

[18] Acad Med Rio de Janeiro, Div Med, Rio De Janeiro, Brazil

[19] Hosp La Paz, Dept Allergy, Inst Hlth Res, Madrid, Spain

[20] CIBER Resp Dis CIBERES, Madrid, Spain

[21] Med Univ Vienna, Ctr Pathophysiol Infectiol & Immunol, Dept Pathophysiol & Allergy Res, Div Immunopathol, Vienna, Austria

[22] Luxembourg Inst Hlth, Lab Immunogenet & Allergol, Dept Infect & Immun, Luxembourg, Luxembourg

[23] Univ Genoa, IRCCS AOU San Martino IST, Allergy & Resp Dis Clin, Genoa, Italy

[24] Imperial Coll London, NHLI, Sect Allergy & Clin Immunol, London, England

[25] Childrens Mercy Hosp, Div Allergy Immunol, Kansas City, MO 64108 USA

[26] Imperial Coll London, Dept Paediat, London, England

[27] Mahidol Univ, Ramathibodi Hosp, Dept Pediat, Div Pediat Allergy Immunol Rheumatol, Bangkok, Thailand

来源：

WORLD ALLERGY ORGANIZATION JOURNAL | 2017年 / 10卷

基金：

英国医学研究理事会;

关键词：

HOUSE-DUST-MITE; GENOME-WIDE ASSOCIATION; DERMATOPHAGOIDES-PTERONYSSINUS ACARI; SUBLINGUAL ALLERGEN IMMUNOTHERAPY; THYMIC STROMAL LYMPHOPOIETIN; CD14 PROMOTER POLYMORPHISMS; ATOPIC-DERMATITIS; IMMUNOGLOBULIN-E; DOUBLE-BLIND; IGE SENSITIZATION;

D O I：

10.1186/s40413-017-0145-4

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Since mite allergens are the most relevant inducers of allergic diseases worldwide, resulting in significant morbidity and increased burden on health services, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), formed by the American Academy of Allergy, Asthma and Immunology (AAAAI), the American College of Allergy, Asthma and Immunology (ACAAI), the European Academy of Allergy and Clinical Immunology (EAACI), and the World Allergy Organization (WAO), has proposed to issue an International Consensus (ICON) on the clinical consequences of mite hypersensitivity. The objectives of this document are to highlight aspects of mite biology that are clinically relevant, to update the current knowledge on mite allergens, routes of sensitization, the genetics of IgE responses to mites, the epidemiologic aspects of mite hypersensitivity, the clinical pictures induced by mites, the diagnosis, specific immunotherapeutic approaches, and prevention.

引用

页数：26

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