Paraneoplastic optic neuropathy secondary to adenocarcinoma of the lung

被引：6

作者：

Yap, Jin Yi ^{[1
,2
]}

Hitam, Wan-Hazabbah Wan ^{[3
]}

Halim, Sanihah Abdul ^{[4
]}

Masnon, Nurul Ain ^{[5
]}

机构：

[1] Univ Sci Malaysia, Sch Med Sci, Ophthalmol, Kubang Kerian, Kelantan, Malaysia

[2] Univ Malaysia Sabah, Surg Dept, Kota Kinabalu, Sabah, Malaysia

[3] Univ Sci Malaysia, Hlth Campus, Kubang Kerian, Malaysia

[4] Univ Sci Malaysia, Dept Med, Kesihatan Campus, Kubang Kerian, Kelantan, Malaysia

[5] Univ Sci Malaysia, Dept Ophthalmol, Kesihatan Campus, Kubang Kerian, Kelantan, Malaysia

来源：

BMJ CASE REPORTS | 2021年 / 14卷 / 05期

关键词：

cancer intervention; neuro-oncology; neuro-ophthalmology; lung cancer (oncology);

D O I：

10.1136/bcr-2021-242082

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe an uncommon cause of paraneoplastic optic neuropathy in adenocarcinoma of the lung. A 45-year-old healthy woman presented with seizure and encephalitis, followed by an acute visual loss in both eyes for 1 week. Her visual acuity was no perception of light in the right eye and hand movement in the left eye. There was a generalised restriction of extraocular muscle movements in both eyes. Funduscopy showed a bilateral pale optic disc. A paraneoplastic antigen autoimmune profile showed a positive anti-CV2/CRMP-5 antibody. CT of the thorax revealed the presence of right apical lung mass, confirmed to be adenocarcinoma through a biopsy. She was scheduled for lung lobectomy and chemotherapy. Unfortunately, her health deteriorated and she passed away eventually.

引用

页数：4

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