Maternal serum pregnancy-associated plasma protein-A concentration at 11-14 weeks of gestation of women with common congenital anatomic uterine abnormalities

被引:0
作者
Sotiriou, Sotirios [1 ]
Satra, Maria [2 ]
Vamvakopoulou, Dimitra N. [3 ]
Sofoudis, Chrisostomos [4 ]
Simou, Aikaterini [5 ]
Kilindris, Thomas [6 ]
Sidiropoulos, Andreas [2 ]
Kakavas, Konstantinos, V [7 ]
Garas, Antonis [5 ]
Skentou, Hara [1 ]
Vamvakopoulos, Nikos C. [2 ]
Daponte, Alexandros [5 ]
机构
[1] Univ Thessaly, Fac Med, Sch Hlth Sci, Lab Histol & Embryol, GR-41500 Larisa, Greece
[2] Univ Thessaly, Fac Med, Sch Hlth Sci, Lab Biol, GR-41500 Larisa, Greece
[3] Univ Thessaly, Fac Med, Sch Hlth Sci, Dept Pediat & Neonatol, GR-41500 Larisa, Greece
[4] Konstandopoulio Gen Hosp, Dept Obstet & Gynecol, GR-11472 Athens, Greece
[5] Univ Thessaly, Fac Med, Sch Hlth Sci, Dept Obstet & Gynaecol, GR-41500 Larisa, Greece
[6] Univ Thessaly, Fac Med, Sch Hlth Sci, Lab Med Informat, GR-41500 Larisa, Greece
[7] Univ Thessaly, Dept Environm, Lab Environm Qual & Human Hlth, GR-41500 Larisa, Greece
关键词
Pregnancy-associated plasma protein A; PAPP-A; Congenital anatomic uterine abnormalities; AUA; INTRAUTERINE GROWTH RESTRICTION; HUMAN CHORIONIC-GONADOTROPIN; PAPP-A; NUCHAL TRANSLUCENCY; PREECLAMPSIA; BETA; PREDICTION; RISK;
D O I
10.31083/j.ceog.2021.02.2319
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives: To evaluate maternal serum pregnancy-associated plasma protein-A (PAPP-A) levels at 11-14 weeks of gestation in women with common congenital anatomic uterine abnormalities (AUAs). Methods: First trimester screening markers were compared between 12 AUA pregnancies and 60 age matched controls. Results: PAPP-A level and birth weight were significantly lower in AUA compared to control pregnancies (P < 0.001). Conclusion: Our findings suggest that AUA pregnancies are associated with low first trimester maternal serum PAPP-A concentrations.
引用
收藏
页码:343 / 346
页数:4
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