Neoadjuvant systemic treatment for breast cancer in Italy: The Italian Society of Surgical Oncology (SICO) Breast Oncoteam survey

被引：6

作者：

Vicini, E. ^{[1
]}

Invento, A. ^{[2
]}

Cuoghi, M. ^{[3
]}

Bafile, A. ^{[4
]}

Battaglia, C. ^{[5
]}

Biglia, N. ^{[6
]}

Busani, M. ^{[7
]}

Bussone, R. ^{[8
]}

Cianchetti, E. ^{[9
]}

Caruso, F. ^{[10
]}

Cucchi, M. C. ^{[3
]}

Dessena, M. ^{[11
]}

Di Filippo, F. ^{[12
]}

Fabi, N. ^{[12
]}

Folli, S. ^{[13
]}

Friedman, D. ^{[14
]}

Macellari, G. ^{[15
]}

Mainente, P. ^{[16
]}

Murgo, R. ^{[17
]}

Neri, A. ^{[18
]}

Pollini, G. P. ^{[2
]}

Palli, D. ^{[19
]}

Ricci, F. ^{[20
]}

Scalco, G. ^{[21
]}

Taffurelli, M. ^{[22
]}

Trunfio, M. ^{[23
]}

Galimberti, V ^{[1
]}

机构：

[1] European Inst Oncol, Div Breast Surg, Milan, Italy

[2] UOC Breast Unit AOUI Borgo Trento, Verona, Italy

[3] Bellaria USL Bologna, UOSD Chirurg Senol Breast Unit, Bologna, Italy

[4] Osped San Salvatore Coppito, Div Breast Surg, Laquila, Italy

[5] Unit Senol Osped Civile Sanremo, San Remo, Italy

[6] Univ Torino, Osp Mauriziano Umberto 1, Turin, Italy

[7] Az Osp C Poma, SSD Chirurg Senol, Mantua, Italy

[8] Osped Cottolengo, Chirurgia Senol Breast Unit, Turin, Italy

[9] Osped Gaetano Bernabeo, Chirurg Gen Indirizzo Senol, Ortona, CH, Italy

[10] Breast Ctr Humanitas, Catania, Italy

[11] Azienda Osped Brotzu, Osped Oncol, SC Chirurg Sperimentale, Cagliari, Italy

[12] Regina Elena Inst Canc Res, Rome, Italy

[13] Osped GB Morgagni SC Senol, AUSL Romagna, Forli, FC, Italy

[14] Osped Policlin San Martino, UO Chirurg Senol, Genoa, Italy

[15] Osped S Giuseppe, Breast Ctr, Milan, Italy

[16] Osped Alto Vicentino, UOS Senol, ULSS PEDEMONTANA 7, SC Chirurg Gen, Vicenza, Italy

[17] Osped IRCCS Casa Sollievo Sofferenza, UOC Chirurg Senol, San Giovanni Rotondo, FG, Italy

[18] Policlin Le Scotte, Ctr Senol AOU Senese, Siena, Italy

[19] Osped Guglielmo Saliceto, UOSD Chirurgia Senol, Breast Unit, Piacenza, Italy

[20] Sapienza Univ Rome, ASL Latina, Breast Unit, SM Goretti Hosp, Latina, Italy

[21] Osped San Bortolo, UOC Chirurg Gen, UOS Senol Chirurg, Vicenza, Italy

[22] Univ Bologna, Dipartimento Med & Chirurg DIMEC, Policlin St Orsola, Bologna, Italy

[23] Azienda Osped A Cardarelli, Dipartimento Senol Chirurg, Naples, Italy

来源：

EJSO | 2018年 / 44卷 / 08期

关键词：

Neoadjuvant; Breast cancer; Multidisciplinary; Breast surgery; Pathological complete response; PATHOLOGICAL COMPLETE RESPONSE; CONSERVING SURGERY; CHEMOTHERAPY; METAANALYSIS; THERAPY; DISEASE; MULTICENTER; MASTECTOMY; ALLIANCE; OUTCOMES;

D O I：

10.1016/j.ejso.2018.03.018

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The Italian Society of Surgical Oncology (SICO) Breast Oncoteam developed a survey to explore the state of the art of neoadjuvant treatment for breast cancer in Italy, specifically focusing on cases treated during the two-year period 2014-2015. A questionnaire was sent to Italian Breast Units with a minimum of 150 new breast cancer cases treated/year according to the Senonetwork directory and to the SICO Breast Oncoteam Breast Unit network. A total of 23/107 Breast Units submitted the survey, reporting a total amount of 20156 cases of breast carcinoma (17241 invasive, 2915 in situ) treated in the biennium, corresponding approximately to 20% of newly diagnosed breast cancers in Italy. In the United States, medical treatment before surgery for breast cancer is indicated in about 22.7% of newly diagnosed cases according to the National Cancer Database, while a German study reported approximately 20% of cases treated with neoadjuvant therapy. In our survey, a total of 1673/17241 cases (9.7%) were treated with neoadjuvant therapy, ranging from 2.9% to 23.6% according to different centres, showing heterogeneity in neoadjuvant treatment indications, even in multidisciplinary breast units. Better resources should be engaged to achieve a standardised quality indicator for neoadjuvant treatment, and this indicator could be included among the European Society of Breast Cancer Specialists (EUSOMA) quality indicators. In the near future, we plan to develop a second survey to better test improvements in the employment of neoadjuvant therapy after the expiry of the 2016 European Parliament deadline and after the 2017 St. Gallen Conference recommendations. (C) 2018 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

引用

页码：1157 / 1163

页数：7

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