Manipulating the brain with epigenetics

被引：16

作者：

Korzus, Edward ^{[1
]}

机构：

[1] Univ Calif Riverside, Dept Psychol, Riverside, CA 92521 USA

来源：

NATURE NEUROSCIENCE | 2010年 / 13卷 / 04期

关键词：

DNA METHYLATION; MEMORY FORMATION; NERVOUS-SYSTEM; METHYLTRANSFERASES; ACETYLATION; EXPRESSION; NEURONS; MICE;

D O I：

10.1038/nn0410-405

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A study finds that the DNA methylation enzymes Dnmt1 and Dnmt3a are needed to maintain the epigenetic landscape in nondividing, postmitotic neurons and that this process is required for normal learning and memory.

引用

页码：405 / 406

页数：2

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