Polyarteritis Nodosa

被引：54

作者：

Forbess, Lindsy ^{[1
]}

Bannykh, Serguei ^{[2
]}

机构：

[1] Cedars Sinai Med Ctr, Dept Rheumatol, Los Angeles, CA 90048 USA

[2] Cedars Sinai Med Ctr, Dept Pathol, Los Angeles, CA 90048 USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2015年 / 41卷 / 01期

关键词：

Polyarteritis nodosa; Vasculitis; Systemic necrotizing vasculitis; Medium vessel vasculitis; CHURG-STRAUSS-SYNDROME; PRIMARY SYSTEMIC VASCULITIS; POOR-PROGNOSIS FACTORS; MICROSCOPIC POLYANGIITIS; CLASSIFICATION CRITERIA; WEGENERS-GRANULOMATOSIS; CONSENSUS CONFERENCE; DIAGNOSTIC-CRITERIA; NOMENCLATURE; CYCLOPHOSPHAMIDE;

D O I：

10.1016/j.rdc.2014.09.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Polyarteritis nodosa (PAN) is a systemic disease, but variants are cutaneous PAN and single-organ disease. Histologic confirmation of vasculitis in medium-sized arteries is desirable, and biopsies should be obtained from the symptomatic and least invasive sites. Angiography can show multiple microaneurysms in the viscera. Treatment includes high-dose corticosteroids, which are combined with immunosuppressive agents when internal organs are involved and with life-threatening disease. Once remission is achieved, maintenance agents are initiated. PAN is becoming a rare disease. International collaborative efforts are under way to establish better diagnostic and classification for all vasculitides, including PAN.

引用

页码：33 / +

页数：15

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