Astatine-211 imaging by a Compton camera for targeted radiotherapy

被引：18
作者：
Nagao, Yuto [1 ,2 ]
Yamaguchi, Mitsutaka [1 ]
Watanabe, Shigeki [1 ]
Ishioka, Noriko S. [1 ]
Kawachi, Naoki [1 ]
Watabe, Hiroshi [1 ,2 ,3 ]
机构：
[1] Natl Inst Quantum & Radiol Sci & Technol, Takasaki Adv Radiat Res Inst, 1233 Watanuki, Takasaki, Gunma 3701292, Japan
[2] Tohoku Univ, Grad Sch Biomed Engn, Aoba Ku, 6-6-12 Aoba, Sendai, Miyagi 9808579, Japan
[3] Tohoku Univ, Cyclotron & Radioisotope Ctr, Aoba Ku, 6-3 Aoba, Sendai, Miyagi 9808578, Japan
来源：
APPLIED RADIATION AND ISOTOPES | 2018年 / 139卷
关键词：
Astatine-211; Compton camera; Monte Carlo simulation; Targeted radiotherapy; NEUTRON-CAPTURE THERAPY; NUCLEAR-DATA SHEETS; PROMPT GAMMA-RAYS; AT-211; DOSIMETRY; SYSTEM;
D O I：
10.1016/j.apradiso.2018.05.022
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Astatine-211 is a promising radionuclide for targeted radiotherapy. It is required to image the distribution of targeted radiotherapeutic agents in a patient's body for optimization of treatment strategies. We proposed to image At-211 with high-energy photons to overcome some problems in conventional planar or single-photon emission computed tomography imaging. We performed an imaging experiment of a point-like At-211 source using a Compton camera, and demonstrated the capability of imaging At-211 with the high-energy photons for the first time.
引用
收藏
页码：238 / 243
页数：6
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