Humoral immune responses to chicken infectious anemia virus in three strains of chickens in a closed flock

被引：37

作者：

Cardona, C ^{[1
]}

Lucio, B ^{[1
]}

O'Connell, P ^{[1
]}

Jagne, J ^{[1
]}

Schat, KA ^{[1
]}

机构：

[1] Cornell Univ, Coll Vet Med, Unit Avian Hlth, Dept Microbiol & Immunol, Ithaca, NY 14853 USA

来源：

AVIAN DISEASES | 2000年 / 44卷 / 03期

关键词：

chicken infectious anemia virus; circovirus; humoral immunity; immune genetics;

D O I：

10.2307/1593108

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

This is a comparative study on seroconversion to chicken infectious anemia virus (CIAV) in a closed flock of specific-pathogen-free chickens undergoing a natural outbreak and after vaccination of some of these flocks with a commercial, live vaccine. The N2a strain ((BB21)-B-21 haplotype) had the highest seroconversion after natural infection (94%) or vaccination (100%), followed by the P2a strain ((BB19)-B-19) at 75%-82% seroconversion after natural infection and 85% seroconversion after vaccination. The S13 ((BB13)-B-13) chickens were 26% seropositive after natural infection and 75% seropositive after vaccination. N2a chickens with polymerase chain reaction (PCR)-positive tissues were 97% seropositive compared to 80%-83% PCR-positive and seropositive for the P2a chickens and only 8% seropositive and PCR-positive for the S13 chickens. Seroconversion occurred at or near sexual maturity after natural infection in seven flocks studied.

引用

页码：661 / 667

页数：7

共 22 条

[1]

Bulow VV, 1997, DIS POULTRY, P739

[2]

CARDONA CJ, IN PRESS J GEN VIROL

[3] CHARACTERIZATION OF PROTEINS OF CHICKEN INFECTIOUS-ANEMIA VIRUS WITH MONOCLONAL-ANTIBODIES [J].

CHANDRATILLEKE, D ;

OCONNELL, P ;

SCHAT, KA .

AVIAN DISEASES, 1991, 35 (04) :854-862

[4] MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF THE GENOME OF CHICKEN ANEMIA AGENT [J].

CLAESSENS, JAJ ;

SCHRIER, CC ;

MOCKETT, APA ;

JAGT, EHJM ;

SONDERMEIJER, PJA .

JOURNAL OF GENERAL VIROLOGY, 1991, 72 :2003-2006

[5]

FADLY AM, 1994, P INT S INF BURS DIS, P447

[6] Poultry industry strategies for control of immunosuppressive diseases [J].

Fussell, LW .

POULTRY SCIENCE, 1998, 77 (08) :1193-1196

[7] ABROGATION OF AGE-RELATED RESISTANCE TO CHICKEN INFECTIOUS-ANEMIA BY EMBRYONAL BURSECTOMY [J].

HU, LB ;

LUCIO, B ;

SCHAT, KA .

AVIAN DISEASES, 1993, 37 (01) :157-169

[8]

HU LB, 1992, THESIS CORNELL U ITH

[9] IMMUNOGENIC AND PROTECTIVE PROPERTIES OF CHICKEN ANEMIA VIRUS PROTEINS EXPRESSED BY BACULOVIRUS [J].

KOCH, G ;

VANROOZELAAR, DJ ;

VERSCHUEREN, CAJ ;

VANDEREB, AJ ;

NOTEBORN, MHM .

VACCINE, 1995, 13 (08) :763-770

[10] IDENTIFICATION OF THE CHICKEN ANEMIA AGENT, REPRODUCTION OF THE DISEASE, AND SEROLOGICAL SURVEY IN THE UNITED-STATES [J].

LUCIO, B ;

SCHAT, KA ;

SHIVAPRASAD, HL .

AVIAN DISEASES, 1990, 34 (01) :146-153

← 1 2 3 →