Biotransformation of limonene by bacteria, fungi, yeasts, and plants

被引:205
作者
Duetz, WA
Bouwmeester, H
van Beilen, JB
Witholt, B
机构
[1] Plant Res Int, NL-6700 AA Wageningen, Netherlands
[2] ETH Honggerberg, Inst Biotechnol, HPT, CH-8093 Zurich, Switzerland
关键词
D O I
10.1007/s00253-003-1221-y
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The past 5 years have seen significant progress in the field of limonene biotransformation, especially with regard to the regiospecificity of microbial biocatalysts. Whereas earlier only regiospecific biocatalysts for the 1,2 position (limonene-1,2-diol) and the 8-position (alpha-terpineol) were available, recent reports describe microbial biocatalysts specifically hydroxylating the 3-position (isopiperitenol), 6-position (carveol and carvone), and 7-position (perillyl alcohol, perillylaaldehyde, and perillic acid). The present review also includes the considerable progress made in the characterization of plant P-450 limonene hydroxylases and the cloning of the encoding genes.
引用
收藏
页码:269 / 277
页数:9
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