Skeletal Stem Cells in Space and Time

被引：46
作者：
Kassem, Moustapha [1 ,2 ]
Bianco, Paolo [3 ]
机构：
[1] Odense Univ Hosp, Dept Endocrinol, DK-5000 Odense C, Denmark
[2] Univ Copenhagen, Panum Inst, Danish Stem Cell Ctr DanStem, DK-2200 Copenhagen, Denmark
[3] Univ Roma La Sapienza, Dept Mol Med, I-00161 Rome, Italy
来源：
CELL | 2015年 / 160卷 / 1-2期
关键词：
BONE;
D O I：
10.1016/j.cell.2014.12.034
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The nature, biological characteristics, and contribution to organ physiology of skeletal stem cells are not completely determined. Chan et al. and Worthley et al. demonstrate that a stem cell for skeletal tissues, and a system of more restricted, downstream progenitors, can be identified in mice and demonstrate its role in skeletal tissue maintenance and regeneration.
引用
收藏
页码：17 / 19
页数：4
相关论文
共 10 条
  • [1] New factors controlling the balance between osteoblastogenesis and adipogenesis
    Abdallah, Basem M.
    Kassem, Moustapha
    [J]. BONE, 2012, 50 (02) : 540 - 545
  • [2] The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine
    Bianco, Paolo
    Cao, Xu
    Frenette, Paul S.
    Mao, Jeremy J.
    Robey, Pamela G.
    Simmons, Paul J.
    Wang, Cun-Yu
    [J]. NATURE MEDICINE, 2013, 19 (01) : 35 - 42
  • [3] Identification and Specification of the Mouse Skeletal Stem Cell
    Chan, Charles K. F.
    Seo, Eun Young
    Chen, James Y.
    Lo, David
    McArdle, Adrian
    Sinha, Rahul
    Tevlin, Ruth
    Seita, Jun
    Vincent-Tompkins, Justin
    Wearda, Taylor
    Lu, Wan-Jin
    Senarath-Yapa, Kshemendra
    Chung, Michael T.
    Marecic, Owen
    Tran, Misha
    Yan, Kelley S.
    Upton, Rosalynd
    Walmsley, Graham G.
    Lee, Andrew S.
    Sahoo, Debashis
    Kuo, Calvin J.
    Weissman, Irving L.
    Longaker, Michael T.
    [J]. CELL, 2015, 160 (1-2) : 285 - 298
  • [4] Friedenstein AJ., 1988, CIBA F SYMP, P42, DOI 10.1002/9780470513637.ch4
  • [5] Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    Mendez-Ferrer, Simon
    Michurina, Tatyana V.
    Ferraro, Francesca
    Mazloom, Amin R.
    MacArthur, Ben D.
    Lira, Sergio A.
    Scadden, David T.
    Ma'ayan, Avi
    Enikolopov, Grigori N.
    Frenette, Paul S.
    [J]. NATURE, 2010, 466 (7308) : 829 - U59
  • [6] Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development
    Mizoguchi, Toshihide
    Pinho, Sandra
    Ahmed, Jalal
    Kunisaki, Yuya
    Hanoun, Maher
    Mendelson, Avital
    Ono, Noriaki
    Kronenberg, Henry M.
    Frenette, Paul S.
    [J]. DEVELOPMENTAL CELL, 2014, 29 (03) : 340 - 349
  • [7] The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche
    Omatsu, Yoshiki
    Sugiyama, Tatsuki
    Kohara, Hiroshi
    Kondoh, Gen
    Fujii, Nobutaka
    Kohno, Kenji
    Nagasawa, Takashi
    [J]. IMMUNITY, 2010, 33 (03) : 387 - 399
  • [8] Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
    Sacchetti, Benedetto
    Funari, Alessia
    Michienzi, Stefano
    Di Cesare, Silvia
    Piersanti, Stefania
    Saggio, Isabella
    Tagliafico, Enrico
    Ferrari, Stefano
    Robey, Pamela Gehron
    Riminucci, Mara
    Bianco, Paolo
    [J]. CELL, 2007, 131 (02) : 324 - 336
  • [9] Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential
    Worthley, Daniel L.
    Churchill, Michael
    Compton, Jocelyn T.
    Tailor, Yagnesh
    Rao, Meenakshi
    Si, Yiling
    Levin, Daniel
    Schwartz, Matthew G.
    Uygur, Aysu
    Hayakawa, Yoku
    Gross, Stefanie
    Renz, Bernhard W.
    Setlik, Wanda
    Martinez, Ashley N.
    Chen, Xiaowei
    Nizami, Saqib
    Lee, Heon Goo
    Kang, H. Paco
    Caldwell, Jon-Michael
    Asfaha, Samuel
    Westphalen, C. Benedikt
    Graham, Trevor
    Jin, Guangchun
    Nagar, Karan
    Wang, Hongshan
    Kheirbek, Mazen A.
    Kolhe, Alka
    Carpenter, Jared
    Glaire, Mark
    Nair, Abhinav
    Renders, Simon
    Manieri, Nicholas
    Muthupalani, Sureshkumar
    Fox, James G.
    Reichert, Maximilian
    Giraud, Andrew S.
    Schwabe, Robert F.
    Pradere, Jean-Phillipe
    Walton, Katherine
    Prakash, Ajay
    Gumucio, Deborah
    Rustgi, Anil K.
    Stappenbeck, Thaddeus S.
    Friedman, Richard A.
    Gershon, Michael D.
    Sims, Peter
    Grikscheit, Tracy
    Lee, Francis Y.
    Karsenty, Gerard
    Mukherjee, Siddhartha
    [J]. CELL, 2015, 160 (1-2) : 269 - 284
  • [10] Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow
    Zhou, Bo O.
    Yue, Rui
    Murphy, Malea M.
    Peyer, James G.
    Morrison, Sean J.
    [J]. CELL STEM CELL, 2014, 15 (02) : 154 - 168
1