Contrast-enhanced power Doppler ultrasound in the diagnosis and follow-up of inflammatory abdominal masses in Crohn's disease

Objective The purpose of this study was to evaluate the potential usefulness of contrast-enhanced power Doppler ultrasound in the detection and follow-up of local complications (phlegmon and abscess) in Crohn's disease. Methods With this aim, 28 patients with suspected abdominal inflammatory mass were examined with power Doppler ultrasound before and after intravenous administration of the ultrasound contrast agent Levovist, with evaluation of vascularity within and/or around the inflammatory mass. Colour Doppler flow was characterized as clearly visible, minimally visible or absent. All the patients underwent a post-contrast computed tomography exam. Results Power Doppler ultrasound, after administration of contrast medium, allows the detection of small inflammatory masses in Crohn's disease, particularly those under 2 cm in diameter, when compared with computed tomography. Conclusions We conclude that contrast-enhanced power Doppler ultrasound is a sensitive method for the detection of small abdominal inflammatory masses and for differential diagnosis between phlegmon and abscess.