Pregnancy, postpartum autoimmune thyroiditis, and autoimmune hypophysitis: Intimate relationships

被引：15

作者：

Landek-Salgado, Melissa A. ^{[1
]}

Gutenberg, Angelika ^{[2
]}

Lupi, Isabella ^{[3
]}

Kimura, Hiroaki ^{[1
]}

Mariotti, Stefano ^{[4
]}

Rose, Noel R. ^{[1
,5
]}

Caturegli, Patrizio ^{[1
,5
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA

[2] Univ Gottingen, Dept Neurosurg, Gottingen, Germany

[3] Univ Pisa, Dept Endocrinol & Metab, Pisa, Italy

[4] Univ Cagliari, Dept Med Sci, I-09124 Cagliari, Italy

[5] Johns Hopkins Bloomberg Sch Publ Hlth, Feinstone Dept Mol Microbiol & Immunol, Baltimore, MD USA

来源：

AUTOIMMUNITY REVIEWS | 2010年 / 9卷 / 03期

关键词：

Pregnancy; Hypophysitis; Postpartum thyroiditis; REGULATORY T-CELLS; NATURAL-KILLER-CELLS; LYMPHOCYTIC HYPOPHYSITIS; PERIPHERAL-BLOOD; PITUITARY-GLAND; DYSFUNCTION; DISEASE; FETUS; ANTIBODIES; TOLERANCE;

D O I：

10.1016/j.autrev.2009.06.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Autoimmune diseases comprise a group of about 85 heterogeneous conditions that can affect virtually any organ and tissue in the body. Many autoimmune diseases change significantly during pregnancy: some ameliorate, some worsen, and others are unaffected. Two autoimmune diseases present prominently in relation to pregnancy: postpartum autoimmune thyroiditis and autoimmune hypophysitis. This article will review the current state of knowledge of the immunological changes that occur during normal pregnancy, and will explore the striking temporal association with pregnancy observed in thyroiditis and hypophysitis. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：153 / 157

页数：5

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