Severe acute pharyngotonsillitis due to herpes simplex virus type 2 in a young woman

被引：7

作者：

Rosain, Jeremie ^{[1
]}

Froissart, Antoine ^{[2
]}

Estrangin, Elisabeth ^{[3
]}

Rozenberg, Flore ^{[1
]}

机构：

[1] Hop Cochin, AP HP, Serv Virol, F-75014 Paris, France

[2] CHI Creteil, Serv Med Interne, Creteil, France

[3] CHI Creteil, Lab Microbiol, Creteil, France

来源：

JOURNAL OF CLINICAL VIROLOGY | 2015年 / 63卷

关键词：

HSV-2; Pharyngotonsillitis; Primary infection; Sexually transmitted disease; PRIMARY INFECTION; MANIFESTATIONS; VIREMIA;

D O I：

10.1016/j.jcv.2014.12.013

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Whereas herpes simplex virus type 1 (HSV-1) is a recognized cause of acute oropharyngeal infection in young adults, HSV-2 infections are mostly associated with genital symptoms. We report a case of acute and prolonged febrile ulcerative pharyngotonsillitis with inflammatory syndrome which persisted despite antibiotic therapy for 8 days and required hospitalization in an 18-year old immune competent and sexually active female patient. HSV-2 was evidenced in tonsillar samples and blood by real time PCR, and HSV type-specific serology showed HSV-2 primary infection. Despite delayed diagnosis, acyclovir treatment led to rapid clinical improvement. This case highlights HSV-2 as an unusual cause of pharyngotonsillitis that should be reminded in sexually active patients. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：63 / 65

页数：3

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