Probing biopolymers with the atomic force microscope: A review

被引：53

作者：

Hansma, HG ^{[1
]}

Pietrasanta, LI

Auerbach, ID

Sorenson, C

Golan, R

Holden, PA

机构：

[1] Univ Calif Santa Barbara, Dept Phys, Santa Barbara, CA 93106 USA

[2] Univ Calif Santa Barbara, Donald Bren Sch Environm Sci & Management, Santa Barbara, CA 93106 USA

来源：

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 2000年 / 11卷 / 07期

关键词：

scanning force microscopy; laminin; DNA; neurofilaments; Pseudomonas putida biofilms;

D O I：

10.1163/156856200743940

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This short review presents an overview of atomic force microscopy (AFM) of biopolymers and specific examples of some of the biopolymers that have been analyzed by AFM. These specific examples include extracellular polymeric substances on the surfaces of bacterial biofilms; condensed DNA, DNA constructs, and DNA-protein interactions. In addition, two examples are presented for AFM analyses of proteins: laminin flexing its arms in solution and neurofilaments entropically brushing away the space around themselves.

引用

页码：675 / 683

页数：9

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