Experience With 750 Consecutive Laparoscopic Donor Nephrectomies-Is it Time to Use a Standardized Classification of Complications?

被引:45
作者
Harper, J. D. [1 ]
Breda, A. [1 ]
Leppert, J. T. [1 ]
Veale, J. L. [1 ]
Gritsch, H. A. [1 ]
Schulam, P. G. [1 ]
机构
[1] Univ Calif Los Angeles, Med Ctr, Dept Urol, Los Angeles, CA 90024 USA
关键词
kidney transplantation; laparoscopy; nephrectomy; postoperative complications; intraoperative complications; PROPOSED CLASSIFICATION; LIVE; MANAGEMENT; ANALGESIA; MORBIDITY; OUTCOMES; SAFETY;
D O I
10.1016/j.juro.2010.01.021
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: Laparoscopic living donor nephrectomy offers patients the benefits of decreased morbidity and improved cosmesis, while maintaining equivalent graft outcomes and complication rates similar to those of open donor surgery. With expressed concern for donor safety, using a standardized complication scale would allow combining data in a donor registry so potential donors could be adequately followed and counseled. We present the largest series to our knowledge of laparoscopic living donor nephrectomy by a single surgeon. Materials and Methods: The institution's initial 750 laparoscopic living donor nephrectomies were included in the study, and a retrospective and prospective chart and database analysis was performed. Results: Mean donor age was 40.5 years and average body mass index was 25.7 kg/m(2). There were 175 patients (23%) with 2 or more renal arteries while 161 (21.5%) had early arterial bifurcations. There were 3 open conversions (0.4%) and the overall complication rate was 5.46%. Median hospital stay was 1 day and the readmission rate was 1.2%. There were 5 reoperations (0.67%), none of which was for the control of bleeding. No patients required a blood transfusion and there were no mortalities. Using a modified Clavien classification of complications for living donor nephrectomy 65.8% were grade 1, 31.7% grade 2 (12.2% grade 2a, 14.6% grade 2b, 4.9% grade 2c) and 2.4% grade 3. There were no grade 4 complications. Conclusions: With appropriate patient selection and operative experience, laparoscopic living donor nephrectomy is a safe procedure associated with low morbidity. The use of a standardized complication system specific for this procedure is encouraged and could aid in counseling potential donors in the future.
引用
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页码:1941 / 1946
页数:6
相关论文
共 28 条
[1]   Complications of laparoscopic living donor nephrectomy and their management: The UCLA experience [J].
Breda, A. ;
Veale, J. ;
Liao, J. ;
Schulam, P. G. .
UROLOGY, 2007, 69 (01) :49-52
[2]   Association of bowel rest and ketorolac analgesia with short hospital stay after laparoscopic donor nephrectomy [J].
Breda, Alberto ;
Bui, Matthew H. ;
Liao, Joseph C. ;
Schulam, Peter G. .
UROLOGY, 2007, 69 (05) :828-831
[3]   Incidence of ureteral strictures after laparoscopic donor nephrectomy [J].
Breda, Alberto ;
Bui, Matthew H. ;
Liao, Joseph C. ;
Gritsch, H. Albin ;
Schulam, Peter G. .
JOURNAL OF UROLOGY, 2006, 176 (03) :1065-1068
[4]   Major and minor injuries during the creation of pneumoperitoneum - A multicenter study on 12,919 cases [J].
Catarci, M ;
Carlini, M ;
Gentileschi, P ;
Santoro, E .
SURGICAL ENDOSCOPY-ULTRASOUND AND INTERVENTIONAL TECHNIQUES, 2001, 15 (06) :566-569
[5]   Laparoscopic donor nephrectomy - Intraoperative safety, immediate morbidity, and delayed complications with 500 cases [J].
Chin, Edward H. ;
Hazzan, David ;
Herron, Daniel M. ;
Gaetano, John N. ;
Ames, Scott A. ;
Bromberg, Jonathan S. ;
Edye, Michael .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2007, 21 (04) :521-526
[6]  
CLAVIEN PA, 1992, SURGERY, V111, P518
[7]   LAPAROSCOPIC NEPHRECTOMY - INITIAL CASE-REPORT [J].
CLAYMAN, RV ;
KAVOUSSI, LR ;
SOPER, NJ ;
DIERKS, SM ;
MERETYK, S ;
DARCY, MD ;
ROEMER, FD ;
PINGLETON, ED ;
THOMSON, PG ;
LONG, SR .
JOURNAL OF UROLOGY, 1991, 146 (02) :278-282
[8]   Classification of surgical complications - A new proposal with evaluation in a cohort of 6336 patients and results of a survey [J].
Dindo, D ;
Demartines, N ;
Clavien, PA .
ANNALS OF SURGERY, 2004, 240 (02) :205-213
[9]   200 consecutive hand assisted laparoscopic donor nephrectomies: Evolution of operative technique and outcomes [J].
Fisher, PC ;
Montgomery, JS ;
Johnston, WK ;
Wolf, JS .
JOURNAL OF UROLOGY, 2006, 175 (04) :1439-1443
[10]   Ketorolac-based analgesia improves outcomes for living kidney donors [J].
Freedland, SJ ;
Blanco-Yarosh, M ;
Sun, JC ;
Hale, SJ ;
Elashoff, DA ;
Litwin, MS ;
Smith, RB ;
Rajfer, J ;
Gritsch, HA .
TRANSPLANTATION, 2002, 73 (05) :741-745