An asymmetric dihydroxylation route to (2S,3S)-3-hydroxypipecolic acid

被引：31
作者：
Bodas, MS [1 ]
Kumar, P [1 ]
机构：
[1] Natl Chem Lab, Div Organ Chem Technol, Pune 411008, Maharashtra, India
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 46期
关键词：
D O I：
10.1016/j.tetlet.2004.09.123
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A concise enantioselective synthesis of (2S,3S)-3-hydroxypipecolic acid 1 starting from 1,4-butanediol using Sharpless asymmetric dihydroxylation and the regioselective nucleophilic opening of a cyclic sulfate as the key steps is described. (C) 2004 Elsevier Ltd. All rights reserved.
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收藏
页码：8461 / 8463
页数：3
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