Cervix Cancer in Sub-Saharan Africa: An Assessment of Cervical Cancer Management

被引:33
作者
Burt, Lindsay M. [1 ]
McCormak, Mary [13 ]
Lecuru, Fabrice [2 ]
Kanyike, Daniel M. [3 ]
Bvochora-Nsingo, Memory [4 ]
Ndlovu, Ntokozo [5 ]
Scott, Aba A. [6 ]
Anorlu, Rose, I [7 ]
Sharma, Vinay [8 ]
Plante, Marie [9 ]
Nyongesa, Catherine [10 ]
Tigeneh, Wondemagegnehu [11 ]
Fakie, Nazia [12 ]
Suneja, Gita [1 ]
Gaffney, David K. [1 ]
机构
[1] Univ Utah, Huntsman Canc Inst, Dept Radiat Oncol, Salt Lake City, UT 84112 USA
[2] Georges Pompidou European Hosp, Paris, France
[3] Uganda Canc Inst, Kampala, Uganda
[4] Gaborone Private Hosp, Gaborone, Botswana
[5] Univ Zimbabwe, Parirenyatwa Hosp Harare, Coll Hlth Sci, Harare, Zimbabwe
[6] Korle Bu Teaching Hosp, Accra, Ghana
[7] Lagos Univ, Univ Lagos, Teaching Hosp, Lagos, Nigeria
[8] Univ Witwatersrand, Charlotte Maxeke Johannesburg Acad Hosp, Pk Town, South Africa
[9] Hotel Dieu Quebec, Quebec City, PQ, Canada
[10] Kenyatta Natl Hosp, Texas Ctr, Nairobi, Kenya
[11] Addis Ababa Univ, Coll Hlth Sci, Addis Ababa, Ethiopia
[12] Univ Cape Town, Cape Town, South Africa
[13] Univ Coll Hosp London, London, England
关键词
D O I
10.1200/GO.20.00079
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PURPOSE Underdeveloped nations carry the burden of most cervical cancer, yet access to adequate treatment can be challenging. This report assesses the current management of cervical cancer in sub-Saharan Africa to better understand the needs of underdeveloped nations in managing cervical cancer. METHODS A pre- and postsurvey was sent to all centers participating in the Cervical Cancer Research Network's 4th annual symposium. The pre-and postsurvey evaluated human papillomavirus and HIV screening, resources available for workup and/or treatment, treatment logistics, outcomes, and enrollment on clinical trials. Descriptive analyses were performed on survey responses. RESULTS Twenty-nine centers from 12 sub-Saharan countries saw approximately 300 new cases of cervical cancer yearly. Of the countries surveyed, 55% of countries had a human papillomavirus vaccination program and 30% (range, 0%-65%) of women in each region were estimated to have participated in a cervical cancer screening program. In the workup of patients, 43% of centers had the ability to obtain a positron emission tomography and computed tomography scan and 79% had magnetic resonance imaging capabilities. When performing surgery, 88% of those centers had a surgeon with an expertise in performing oncological surgeries. Radiation therapy was available at 96% of the centers surveyed, and chemotherapy was available in 86% of centers. Clinical trials were open at 4% of centers. CONCLUSION There have been significant advancements being made in screening, workup, and management of patients with cervical cancer in sub-Saharan Africa; yet, improvement is still needed. Enrollment in clinical trials remains a struggle. Participants would like to enroll patients on clinical trials with Cervical Cancer Research Network's continuous support. (C) 2021 by American Society of Clinical Oncology
引用
收藏
页码:173 / 182
页数:10
相关论文
共 16 条
  • [1] Utility of PET-CT to evaluate retroperitoneal lymph node metastasis in advanced cervical cancer: Results of ACRIN6671/GOG0233 trial
    Atri, Mostafa
    Zhang, Zheng
    Dehdashti, Farrokh
    Lee, Susanna I.
    Ali, Shamshad
    Marques, Helga
    Koh, Wui-Jin
    Moore, Kathleen
    Landrum, Lisa
    Kim, Jae Weon
    DiSilvestro, Paul
    Eisenhauer, Eric
    Schnell, Frederick
    Gold, Michael
    [J]. GYNECOLOGIC ONCOLOGY, 2016, 142 (03) : 413 - 419
  • [2] Expanding global access to radiotherapy
    Atun, Rifat
    Jaffray, David A.
    Barton, Michael B.
    Bray, Freddie
    Baumann, Michael
    Vikram, Bhadrasain
    Hanna, Timothy P.
    Knaul, Felicia M.
    Lievens, Yolande
    Lui, Tracey Y. M.
    Milosevic, Michael
    O'Sullivan, Brian
    Rodin, Danielle L.
    Rosenblatt, Eduardo
    Van Dyk, Jacob
    Yap, Mei Ling
    Zubizarreta, Eduardo
    Gospodarowicz, Mary
    [J]. LANCET ONCOLOGY, 2015, 16 (10) : 1153 - 1186
  • [3] Challenges and Prospects for Providing Radiation Oncology Services in Africa
    Balogun, Onyinye
    Rodin, Danielle
    Ngwa, Wilfred
    Grover, Surbhi
    Longo, John
    [J]. SEMINARS IN RADIATION ONCOLOGY, 2017, 27 (02) : 184 - 188
  • [4] Prevention of Cervical Cancer in Sub-Saharan Africa: The Advantages and Challenges of HPV Vaccination
    Black, Eleanor
    Richmond, Robyn
    [J]. VACCINES, 2018, 6 (03):
  • [5] Neoadjuvant Chemotherapy With Cisplatin and Gemcitabine Followed by Chemoradiation Versus Chemoradiation for Locally Advanced Cervical Cancer: A Randomized Phase II Trial
    da Costa, Samantha Cabral S.
    Bonadio, Renata Colombo
    Gabrielli, Flavia Carolina G.
    Aranha, Andrea S.
    Dias Genta, Maria Luiza N.
    Miranda, Vanessa C.
    de Freitas, Daniela
    Abdo Filho, Elias
    Ferreira, Patricia A. O.
    Machado, Karime K.
    Scaranti, Mariana
    Carvalho, Heloisa de A.
    Estevez-Diz, Maria Del Pilar
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (33) : 3124 - +
  • [6] Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis
    Drolet, Melanie
    Benard, Elodie
    Perez, Norma
    Brisson, Marc
    Boily, Marie-Claude
    Ali, Hammad
    Baldo, Vincenzo
    Brassard, Paul
    Brotherton, Julia M. L.
    Callander, Denton
    Checchi, Marta
    Chow, Eric P. F.
    Cocchio, Silvia
    Dalianis, Tina
    Deeks, Shelley L.
    Dehlendorff, Christian
    Donovan, Basil
    Fairley, Christopher K.
    Flagg, Elaine W.
    Gargano, Julia W.
    Garland, Suzanne M.
    Grun, Nathalie
    Hansen, Bo T.
    Harrison, Christopher
    Herweijer, Eva
    Imburgia, Teresa M.
    Johnson, Anne M.
    Kahn, Jessica A.
    Kavanagh, Kimberley
    Kjaer, Susanne K.
    Kliewer, Erich V.
    Liu, Bette
    Machalek, Dorothy A.
    Markowitz, Lauri
    Mesher, David
    Munk, Christian
    Niccolai, Linda
    Nygard, Mari
    Ogilvie, Gina
    Oliphant, Jeannie
    Pollock, Kevin G.
    Purrinos-Hermida, Maria Jesus
    Smith, Megan A.
    Steben, Marc
    Soderlund-Strand, Anna
    Sonnenberg, Pam
    Sparen, Par
    Tanton, Clare
    Wheeler, Cosette M.
    Woestenberg, Petra J.
    [J]. LANCET, 2019, 394 (10197) : 497 - 509
  • [7] Grover S, 2017, J GLOB ONCOL, V3, P666, DOI 10.1200/JGO.2016.006353
  • [8] Grover S, 2017, GYNECOL ONCOL REP, V19, P5, DOI 10.1016/j.gore.2016.11.007
  • [9] Cost-effectiveness analysis of the introduction of the human papillomavirus vaccine in Honduras
    Molina Aguilar, Ida Berenice
    Otilia Mendoza, Lourdes
    Garcia, Odalys
    Diaz, Iris
    Figueroa, Jacqueline
    Maria Duarte, Rosa
    Perdomo, Gabriel
    Garcia, Ana Gabriela Felix
    Janusz, Cara Bess
    [J]. VACCINE, 2015, 33 : A167 - A173
  • [10] Risk of high-grade squamous intraepithelial lesion in HIV-infected adolescents
    Moscicki, AB
    Ellenberg, JH
    Crowley-Nowick, P
    Darragh, TM
    Xu, JH
    Fahrat, S
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2004, 190 (08) : 1413 - 1421