Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes

被引:634
作者
Baidoun, Firas [1 ]
Elshiwy, Kholoud [2 ]
Elkeraie, Yasmine [3 ]
Merjaneh, Zahi [1 ]
Khoudari, George [1 ]
Sarmini, Muhammad Talal [1 ]
Gad, Mohamed [4 ]
Al-Husseini, Muneer [5 ]
Saad, Anas [6 ]
机构
[1] Cleveland Clin Fdn, Dept Hosp Med, Cleveland, Egypt
[2] Ain Shams Univ, Fac Med, Cairo, Egypt
[3] Alexandria Univ, High Inst Publ Hlth, Alexandria, Egypt
[4] Cleveland Clin Fdn, Dept Internal Med, Cleveland, OH USA
[5] Ascens St John Hosp, Dept Med, Detroit, MI USA
[6] Cleveland Clin Fdn, Inst Heart & Vasc, Dept Cardiovasc Med, Cleveland, OH 44195 USA
关键词
Colorectal cancer; epidemiology; incidence; mortality; demographic; prognosis; FAMILIAL ADENOMATOUS POLYPOSIS; INFLAMMATORY-BOWEL-DISEASE; RISK-FACTORS; ULCERATIVE-COLITIS; LYNCH-SYNDROME; UNITED-STATES; COLON-CANCER; FOLLOW-UP; GENDER-DIFFERENCES; ADJUVANT THERAPY;
D O I
10.2174/1389450121999201117115717
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer related deaths in the world with an estimated number of 1.8 million new cases and about 881,000 deaths worldwide in 2018. The epidemiology of CRC varies significantly between different regions in the world as well as between different age, gender and racial groups. Multiple factors are involved in this variation, including risk factor exposure, demographic variations in addition to genetic susceptibility and genetic mutations and their effect on the prognosis and treatment response. In this mini-review, we discuss the recent epidemiological trend including the incidence and mortality of colorectal cancer worldwide and the factors affecting these trends.
引用
收藏
页码:998 / 1009
页数:12
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