UVA and UVB wavebands modulate expression of FasL in mouse skin epidermis

被引：3
|
作者：
Shen, J [1 ]
Bao, S [1 ]
Reeve, VE [1 ]
机构：
[1] Univ Sydney, Dept Vet Anat & Pathol, Sydney, NSW 2006, Australia
来源：
REDOX REPORT | 2000年 / 5卷 / 2-3期
关键词：
D O I：
10.1179/135100000101535546
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In our previous report, we observed different cytokine modulation in mouse epidermis by the UVA and UVB wavebands. In the present investigations, the effects of irradiation with UVA and UVB on the Fas(CD95)/FasL system have been studied because apoptosis mediated by the interaction between Fas and Fast has been suggested recently to be associated with UVB-induced immunosuppression in mouse skin. Our results show that UVA irradiation following UVB irradiation has the ability to reduce the up-regulation of FasL expression in mouse skin resulting from the UVB irradiation.
引用
收藏
页码：154 / 155
页数：2
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