Effect of Anodal Transcranial Direct Current Stimulation on Autism: A Randomized Double-Blind Crossover Trial

被引：86

作者：

Amatachaya, Anuwat ^{[1
]}

Auvichayapat, Narong ^{[2
]}

Patjanasoontorn, Niramol ^{[3
]}

Suphakunpinyo, Chanyut ^{[2
]}

Ngernyam, Niran ^{[1
]}

Aree-uea, Benchaporn ^{[1
]}

Keeratitanont, Keattichai ^{[1
]}

Auvichayapat, Paradee ^{[1
]}

机构：

[1] Khon Kaen Univ, Fac Med, Dept Physiol, Khon Kaen 40002, Thailand

[2] Khon Kaen Univ, Fac Med, Dept Pediat, Khon Kaen 40002, Thailand

[3] Khon Kaen Univ, Fac Med, Dept Psychiat, Khon Kaen 40002, Thailand

来源：

BEHAVIOURAL NEUROLOGY | 2014年 / 2014卷

关键词：

HIGH-FUNCTIONING AUTISM; FUSIFORM FACE AREA; RATING-SCALE CARS; SPECTRUM DISORDERS; MAGNETIC STIMULATION; ASPERGER-SYNDROME; CHILDHOOD AUTISM; LANGUAGE; CHILDREN; BRAIN;

D O I：

10.1155/2014/173073

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The aim of this study was to evaluate the Childhood Autism Rating Scale ( CARS), Autism Treatment Evaluation Checklist (ATEC), and Children's Global Assessment Scale (CGAS) after anodal transcranial direct current stimulation (tDCS) in individuals with autism. Twenty patients with autism received 5 consecutive days of both sham and active tDCS stimulation (1mA) in a randomized double-blind crossover trial over the left dorsolateral prefrontal cortex (F3) for 20 minutes in different orders. Measures of CARS, ATEC, and CGAS were administered before treatment and at 7 days posttreatment. The result showed statistical decrease in CARS score (P < 0.001). ATEC total was decreased from 67.25 to 58 (P < 0.001). CGAS was increased at 7 days posttreatment (P = 0.042). Our study suggests that anodal tDCS over the F3 may be a useful clinical tool in autism.

引用

页数：7

共 48 条

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