TopoGSA: network topological gene set analysis

被引：42

作者：

Glaab, Enrico ^{[1
]}

Baudot, Anais ^{[2
]}

Krasnogor, Natalio ^{[1
]}

Valencia, Alfonso ^{[2
]}

机构：

[1] Univ Nottingham, Sch Comp Sci, Nottingham NG7 2RD, England

[2] CNIO, Struct Biol & Biocomp Program, Madrid, Spain

来源：

BIOINFORMATICS | 2010年 / 26卷 / 09期

基金：

英国生物技术与生命科学研究理事会;

关键词：

CANCER GENES; DATABASE; PROTEINS; BIOLOGY;

D O I：

10.1093/bioinformatics/btq131

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

TopoGSA (Topology-based Gene Set Analysis) is a web-application dedicated to the computation and visualization of network topological properties for gene and protein sets in molecular interaction networks. Different topological characteristics, such as the centrality of nodes in the network or their tendency to form clusters, can be computed and compared with those of known cellular pathways and processes.

引用

页码：1271 / 1272

页数：2

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