Spatial resolution of the Inveon small-animal PET scanner for the entire field of view

被引：5

作者：

Disselhorst, J. A. ^{[1
,2
]}

Boerman, O. C. ^{[1
]}

Oyen, W. J. G. ^{[1
]}

Slump, C. H. ^{[2
]}

Visser, E. P. ^{[1
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Dept Nucl Med, NL-6500 HB Nijmegen, Netherlands

[2] Univ Twente, Inst Tech Med, NL-7500 AE Enschede, Netherlands

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2010年 / 615卷 / 02期

关键词：

Positron emission tomography; Small-animal; Inveon; Spatial resolution; Maximum a posteriori reconstruction;

D O I：

10.1016/j.nima.2010.02.073

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

In high throughput small-animal positron emission tomography (PET) studies, it can be advantageous to scan more than one animal at the same time. To optimally position these animals in the scanner, both sensitivity and spatial resolution have to be known across the entire field of view (FOV). The Siemens Inveon small-animal PET scanner has been characterized according to NEMA NU 4-2008 standards, but the spatial resolution has only been determined in a small portion of the FOV and only for filtered backprojection (FBP). In this study, the spatial resolution in the entire FOV was determined for the Inveon using FBP, ordered subset expectation maximization in 2 dimensions (OSEM2D) and maximum a posteriori (MAP) reconstructions. OSEM2D produced the best spatial resolution in the axial center of the FOV, but MAP outperformed the two other reconstruction algorithms in terms of uniformity of the resolution. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：245 / 248

页数：4

共 6 条

[1]

[Anonymous], 2008, NEMA STAND PUBL

[2] Performance Evaluation of the Inveon Dedicated PET Preclinical Tomograph Based on the NEMA NU-4 Standards [J].

Bao, Qinan ;

Newport, Danny ;

Chen, Mu ;

Stout, David B. ;

Chatziioannou, Arion F. .

JOURNAL OF NUCLEAR MEDICINE, 2009, 50 (03) :401-408

[3]

Cho SH, 2007, IEEE T MED IMAGING, V26, P347, DOI 10.1109/TMI.2006.887378

[4] Performance evaluation of an Inveon PET preclinical scanner [J].

Constantinescu, Cristian C. ;

Mukherjee, Jogeshwar .

PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (09) :2885-2899

[5] NEMA NU 2-2007 performance measurements of the Siemens Inveon™ preclinical small animal PET system [J].

Kemp, Brad J. ;

Hruska, Carrie B. ;

McFarland, Aaron R. ;

Lenox, Mark W. ;

Lowe, Val J. .

PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (08) :2359-2376

[6] Spatial Resolution and Sensitivity of the Inveon Small-Animal PET Scanner [J].

Visser, Eric P. ;

Disselhorst, Jonathan A. ;

Brom, Maarten ;

Laverman, Peter ;

Gotthardt, Martin ;

Oyen, Wim J. G. ;

Boerman, Otto C. .

JOURNAL OF NUCLEAR MEDICINE, 2009, 50 (01) :139-147

← 1 →