Dividing and conquering the variation among variants in EML4-ALK lung cancer

被引：0

作者：

Bivona, Trever G. ^{[1
,2
]}

机构：

[1] Univ Calif San Francisco, Dept Med, San Francisco, CA USA

[2] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA

来源：

TRANSLATIONAL CANCER RESEARCH | 2017年 / 6卷

关键词：

DEPENDENCE; DOMAIN;

D O I：

10.21037/tcr.2017.03.25

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：S369 / S370

页数：2

共 7 条

[1] A framework for understanding and targeting residual disease in oncogene-driven solid cancers [J].

Bivona, Trever G. ;

Doebele, Robert C. .

NATURE MEDICINE, 2016, 22 (05) :472-478

[2] RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer [J].

Hrustanovic, Gorjan ;

Olivas, Victor ;

Pazarentzos, Evangelos ;

Tulpule, Asmin ;

Asthana, Saurabh ;

Blakely, Collin M. ;

Okimoto, Ross A. ;

Lin, Luping ;

Neel, Dana S. ;

Sabnis, Amit ;

Flanagan, Jennifer ;

Chan, Elton ;

Varella-Garcia, Marileila ;

Aisner, Dara L. ;

Vaishnavi, Aria ;

Ou, Sai-Hong I. ;

Collisson, Eric A. ;

Ichihara, Eiki ;

Mack, Philip C. ;

Lovly, Christine M. ;

Karachaliou, Niki ;

Rosell, Rafael ;

Riess, Jonathan W. ;

Doebele, Robert C. ;

Bivona, Trever G. .

NATURE MEDICINE, 2015, 21 (09) :1038-+

[3] Therapeutic Targeting of Anaplastic Lymphoma Kinase in Lung Cancer: A Paradigm for Precision Cancer Medicine [J].

Katayama, Ryohei ;

Lovly, Christine M. ;

Shaw, Alice T. .

CLINICAL CANCER RESEARCH, 2015, 21 (10) :2227-2235

[4] Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain [J].

Richards, Mark W. ;

O'Regan, Laura ;

Roth, Daniel ;

Montgomery, Jessica M. ;

Straube, Anne ;

Fry, Andrew M. ;

Bayliss, Richard .

BIOCHEMICAL JOURNAL, 2015, 467 :529-536

[5] Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain [J].

Richards, Mark W. ;

Law, Edward W. P. ;

Rennalls, La'Verne P. ;

Busacca, Sara ;

O'Regan, Laura ;

Fry, Andrew M. ;

Fennell, Dean A. ;

Bayliss, Richard .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (14) :5195-5200

[6] Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer [J].

Soda, Manabu ;

Choi, Young Lim ;

Enomoto, Munehiro ;

Takada, Shuji ;

Yamashita, Yoshihiro ;

Ishikawa, Shunpei ;

Fujiwara, Shin-ichiro ;

Watanabe, Hideki ;

Kurashina, Kentaro ;

Hatanaka, Hisashi ;

Bando, Masashi ;

Ohno, Shoji ;

Ishikawa, Yuichi ;

Aburatani, Hiroyuki ;

Niki, Toshiro ;

Sohara, Yasunori ;

Sugiyama, Yukihiko ;

Mano, Hiroyuki .

NATURE, 2007, 448 (7153) :561-U3

[7]

Woo CG, 2016, ANN ONCOL

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