Attentionmideficit hyperactivity disorder and brainwderived neurotrophic factor: a speculative hypothesis

被引：31
作者：
Tsai, SJ
机构：
[1] Vet Gen Hosp, Dept Psychiat, Taipei, Taiwan
[2] Natl Yang Ming Univ, Sch Med, Div Psychiat, Taipei 112, Taiwan
来源：
MEDICAL HYPOTHESES | 2003年 / 60卷 / 06期
关键词：
D O I：
10.1016/S0306-9877(03)00052-5
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Brain-derived neurotrophic factor (BDNF) is important for normal neuronal development. Attention-deficit hyperactivity disorder (ADHD), a childhood-onset neurodevelopmental disorder, is characterized by inattention and hyperactivity. Psychostimulants and antidepressants are the agents commonly used for the treatment of ADHD and were also found to elevate central BDNF. It is proposed here that BDNF may play a role in the therapeutic action and pathogenesis of ADHD. This hypothesis may provide a new direction for the treatment and the pathogenesis of ADHD. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：849 / 851
页数：3
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