Ultrasound assisted green synthesis of bis(indol-3-yl)methanes catalyzed by 1-hexenesulphonic acid sodium salt

被引:59
作者
Joshi, Ratnadeep S. [1 ]
Mandhane, Priyanka G. [1 ]
Diwakar, Santosh D. [1 ]
Gill, Charansingh H. [1 ]
机构
[1] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Aurangabad 431004, Maharashtra, India
关键词
1-Hexenesulphonic acid sodium salt; Bis(indol-3-yl)methanes; Ultrasonication; Green synthesis; Aza-Michael; Indole; AMMONIUM METAVANADATE; EFFICIENT SYNTHESIS; ORGANIC-REACTIONS; BIS(INDOLYL)METHANES; WATER;
D O I
10.1016/j.ultsonch.2009.08.015
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
1-Hexenesulphonic acid sodium salt as catalyst for green synthesis of bis(indol-3-yl)methanes was described. The reaction of indole with various aldehydes in water using ultrasound irradiation at ambient temperature for appropriate time using 1-hexenesulphonic acid sodium salt furnish the desired product in good to excellent yield. Utilization of aqueous medium, simple reaction conditions, isolation, and purification makes this manipulation very interesting from an economic and environmental perspective. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:298 / 300
页数:3
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