The First Example of 4,7,8,9-Tetrahydrothieno-[2,3-d]Azocine Synthesis by Domino Reaction of 4-ARYL-4,5,6,7-Tetrahydrothieno[3,2-c]Pyridines with Activated Alkynes

被引：7
|
作者：
Voskressensky, L. G. [1 ]
Borisova, T. N. [1 ]
Chervyakova, T. M. [1 ]
Matveeva, M. D. [1 ]
Galaktionova, D. V. [1 ]
Tolkunov, S. V. [1 ]
Tolkunova, V. S. [2 ]
Eresko, A. B. [2 ]
Varlamov, A. V. [1 ]
机构：
[1] Peoples Friendship Univ Russia, Moscow 117198, Russia
[2] Ukrainian Acad Sci, LM Litvinenko Inst Phys Organ Chem & Coal Chem, UA-83114 Donetsk, Ukraine
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2014年 / 50卷 / 09期
基金：
俄罗斯基础研究基金会;
关键词：
activated alkynes; tetrahydrothieno[2,3-d]azocines; tetrahydrothieno[3,2-c]pyridines; tetrahydropyridine ring expansion domino reaction; DERIVATIVES; INHIBITORS;
D O I：
10.1007/s10593-014-1597-x
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
1-Aryl-substituted tetrahydrothieno[3,2-N]pyridines easily undergo domino reactions with activated alkynes, giving good yields of the corresponding tetrahydrothieno[2,3-d]azocines. The reactions of 1-methyl-substituted tetrahydrothieno[3,2-N]pyridine were more complicated.
引用
收藏
页码：1338 / 1345
页数：8
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