Chiral Metal-Organic Frameworks Bearing Free Carboxylic Acids for Organocatalyst Encapsulation

被引：91

作者：

Liu, Yan ^{[1
,2
]}

Xi, Xiaobing ^{[1
,2
]}

Ye, Chengcheng ^{[1
,2
]}

Gong, Tengfei ^{[1
,2
]}

Yang, Zhiwei ^{[1
,2
]}

Cui, Yong ^{[1
,2
,3
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Shanghai 200240, Peoples R China

[2] Shanghai Jiao Tong Univ, State Key Lab Met Matrix Composites, Shanghai 200240, Peoples R China

[3] Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2014年 / 53卷 / 50期

关键词：

aldol reactions; heterogeneous catalysis; metal-organic frameworks; organocatalysis; porous materials; HETEROGENEOUS ASYMMETRIC CATALYSIS; POROUS MATERIALS; ALDOL REACTION; FUNCTIONALIZATION; DESIGN; EPOXIDATION; SEPARATION; MOLECULE; STRATEGY; LIGAND;

D O I：

10.1002/anie.201408896

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two chiral carboxylic acid functionalized micro- and mesoporous metal-organic frameworks (MOFs) are constructed by the stepwise assembly of triple-stranded heptametallic helicates with six carboxylic acid groups. The mesoporous MOF with permanent porosity functions as a host for encapsulation of an enantiopure organic amine catalyst by combining carboxylic acids and chiral amines in situ through acid-base interactions. The organocatalyst-loaded framework is shown to be an efficient and recyclable heterogeneous catalyst for the asymmetric direct aldol reactions with significantly enhanced stereoselectivity in relative to the homogeneous organocatalyst.

引用

页码：13821 / 13825

页数：5

共 60 条

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[3]

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[4]

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