Gold(I)-Mediated C-H Activation of Arenes

被引：108

作者：

Lu, Pengfei ^{[1
]}

Boorman, Tanya C. ^{[1
]}

Slawin, Alexandra M. Z. ^{[2
]}

Larrosa, Igor ^{[1
]}

机构：

[1] Queen Mary Univ London, Sch Biol & Chem Sci, London E1 4NS, England

[2] Univ St Andrews, Mol Struct Lab, Sch Chem, St Andrews KY16 9ST, Fife, Scotland

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 16期

基金：

英国工程与自然科学研究理事会;

关键词：

ELECTRON-DEFICIENT POLYFLUOROARENES; CATALYZED INTRAMOLECULAR ARYLATION; PROTON-ABSTRACTION MECHANISM; ORGANIC GOLD COMPOUNDS; BOND FORMATION; ORGANOGOLD CHEMISTRY; NONACTIVATED ARENES; COUPLING REACTIONS; TERMINAL ALKYNES; COMPLEXES;

D O I：

10.1021/ja101525w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We demonstrate the first Au(I)-mediated C-H activation of arenes. Au(I) salts undergo C-H activation with electron-poor arenes, in stark contrast to Au(III) salts, which activate electron-rich arenes. This operationally simple and highly regioselective process occurs under very mild conditions and gives access to a variety of Au(I)-arene complexes in excellent yields.

引用

页码：5580 / +

页数：3

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